摘要
目的 探讨小剂量 β受体阻滞剂在难治性心力衰竭治疗中的作用。方法 选择难治性心力衰竭患者 4 3例 ,在洋地黄制剂、利尿剂、血管扩张剂治疗基础上加用小剂量 β受体阻滞剂 ,比较治疗组与对照组患者心功能和左室射血分数的变化。结果 治疗 8周后 ,应用 β受体阻滞剂后治疗组患者有效率为 6 0 4 7% ,显著高于对照组的31 70 % (P <0 0 1) ;治疗组左室射血分数平均为 4 8 6 %± 8 5 % ,显著高于对照组的 4 1 1%± 8 4 % (P <0 0 1)。结论 联用小剂量 β受体阻滞剂可显著改善难治性心衰患者的心功能。
Objective: To investigate the effect of a small dose of β-blockers in the treatment of refractory heart failure Methods: Forty three patients with refractory heart failure received small doses of β-blockers in addition to digitalis, diuretics and vasodilators Change of heart functions and left ventriular ejection fraction (LVEF) were compared with those to whose β-blockers were not given Results: The response rates of heart function and LVEF in the treatment group were markedly higher than those in the control group(P<0 01) within 8 weeks Conclusion:Conventional therapy combined with a small dose of β-blockers may significantly improve heart functions in refractory heart failure
出处
《泰山医学院学报》
CAS
2002年第2期135-136,共2页
Journal of Taishan Medical College
