经鼻持续气道正压通气治疗重症肺炎并呼吸衰竭患儿的疗效被引量：8

Effect of Nasal Continuous Positive Airway Pressure on Severe Pneumonia Complicated by Respiratory Failure in Children

暂未订购

导出

摘要目的探讨重症肺炎并呼吸衰竭患儿采用经鼻持续气道正压通气治疗的临床疗效,并观察其对患儿血气分析的影响。方法回顾性分析92例重症肺炎并呼吸衰竭患儿的临床资料,其中采用常规治疗、面罩吸氧治疗者为对照组(46例);于对照组治疗基础上采用经鼻持续气道正压通气治疗者为观察组(46例)。比较2组治疗前30min、治疗后12h后呼吸频率、心率及血气分析各项指标;采用小儿危重病例评分法(PCIS)评价2组治疗前30min、治疗后12h恢复情况;统计2组治疗期间临床疗效及不良反应情况。结果 2组患儿治疗前后pH值比较差异无统计学意义(P>0.05);2组治疗后PO2、SaO2水平较治疗前明显升高,而PCO2较治疗前明显下降,观察组治疗后PO2、SaO2水平升高程度及PCO2下降程度均优于对照组(均P<0.05)。2组治疗后呼吸频率、心率较治疗前明显下降,观察组呼吸频率及心率下降程度较对照组显著(均P<0.05)。2组患儿治疗后PCIS评分较治疗前明显增加,观察组增加程度更显著(均P<0.05)。观察组治疗总有效率为91.30%,明显高于对照组的67.39%(P<0.05)。结论应用经鼻持续气道正压通气治疗重症肺炎并呼吸衰竭患儿,可有效缓解低氧状态及改善血气分析,有利于促进患儿康复。 Objective To investigate the effect of nasal continuous positive airway pressure on severe pneumonia with respiratory failure and blood gas analysis in children.Methods Clinical data of 92 children with severe pneumonia and respiratory failure were analyzed retrospectively.These children were given conventional therapy and face-mask oxygen administration(control group,n=46)or in combination with nasal continuous positive airway pressure treatment(treatment group,n=46).Respiratory rate,heart rate,blood gas indicators and Pediatric Critical Illness Score(PCIS)were measured 30 minutes before treatment and 12 hours after treatment.In addition,clinical efficacies and adverse reactions were observed in both groups.Results After treatment,the PO2,SaO2 and PCIS score increased(P<0.05),the PCO2,respiratory rate and heart rate decreased(P<0.05),but the pH value did not change in both groups(P>0.05).Furthermore,the increase in PO2,SaO2 and PCIS score and the decrease in PCO2,respiratory rate and heart rate in treatment group were more obvious than those in control group(P>0.05).Moreover,the total effective rate in treatment group(91.30%)was significantly higher than that in control group(67.39%)(P<0.05).Conclusion Nasal continuous positive airway pressure treatment can alleviate hypoxia,improve blood gas indicators and promote recovery in children with severe pneumonia and respiratory failure.

作者谢小丹 XIE Xiao -dan(The First Department of Pediatrics ,Yangjiang People7s Hospital ,Yangjiang 529500 ,Chin)

机构地区阳江市人民医院儿一科

出处《实用临床医学（江西）》 CAS 2017年第3期44-46,66,共4页 Practical Clinical Medicine

关键词重症肺炎呼吸衰竭经鼻持续气道正压通气血气分析儿童 severe pneumonia respiratory failure nasal continuous positive airway pressure blood gas analysis children