摘要
目的比较经鼻持续气道正压通气(NCPAP)方案和纳洛酮联合氨茶碱药物治疗方案治疗继发性新生儿呼吸暂停的疗效差异。方法选择2007年至2012年间至济南军区第一五九中心医院儿科就诊、且采用NCPAP(A)方案或纳洛酮联合氨茶碱(B)方案治疗的继发性新生儿呼吸暂停病例67例,根据治疗方法进行队列分组,分析两组患者的一般情况治及疗后的有效情况、疗效分布和复发情况。结果两组患儿疗前一般资料比较差异无统计学意义。A组治疗起效时间明显优于B组,差异有统计学意义(Z=-3.062,P=0.02),其治疗总体有效率虽高于B组,但差异无统计学意义(P=0.255)。治疗结束后两组均有复发,差异无统计学意义(P均>0.05)。结论 NCPAP方案可在继发性新生儿呼吸暂停治疗过程中较快起效,但其与纳洛酮联合氨茶碱方案的总体疗效、复发情况的差异不明显。
Objective To compare the efficacy of nasal continuous positive airway pressure （NCPAP） treatment and naloxone joint aminophylline drug treatment programs secondary neonatal apnea. Methods From 2007 to 2012, 67 cases of secondary neonatal apnea in our hospital, treated by NAPAP （ group A） or naloxone combined with aminophylline （ group B） were chosen. The general condition, the effect and recurrence of the two groups were analyzed. Results There was no significant difference in the general information between the two groups before treatment. The onset time in group A was significantly better than that in group B group, the difference was statistically significant （ Z = - 3. 062, P = O. 02）. The overall treatment efficiency in group A was higher than that in group B, but the difference was not statistically significant （ P = 0. 255 ）. After the end of treatment, re- currence occured in both groups. There was no significant difference （ P 〉 0. 05）. Conclusion In the secondary neonatal apnea treatment process, NCPAP program has faster onset, but has no sigificant difference in the overall effect and recurrence with Naloxone combined aminophylline compound programs.
出处
《临床医学》
CAS
2013年第10期4-5,共2页
Clinical Medicine
