摘要
Adropin是一种分泌性蛋白,2008年由Kumar等首次在下丘脑性肥胖小鼠肝脏中发现。它由能量平衡相关基因(Enho)编码,是新的维持能量动态平衡的调节多肽。目前研究表明,adropin与肥胖、糖尿病、代谢综合征、脑卒中、高血压、冠心病、心力衰竭等密切相关,本文就adropin在心血管系统方面的研究情况做一综述。
Adropin is a kind of secretory protein, was first identified by Kumar et al in liver of hypothalamie obese mice in 2008. It is encoded by energy balance related gene （ Enho ） and is a new regulating peptide that maintains the balance of energy dynamic. Current studies show that adropin is closely related with obesity, diabetes mellitus, metabolic syndrome, stroke, hypertension, coronary disease, heart failure, ect. Researches about adropin are more and more in recent years, especially in cardiovascular system. However, its function and specific mechanisms in some diseases are controversial and further studies are needed. In this article, the present research situation of adropin in cardiovascular system was reviewed.
出处
《中国心血管杂志》
2017年第2期155-158,共4页
Chinese Journal of Cardiovascular Medicine
