摘要
研究菜籽多肽对改善小鼠睡眠功效的影响。试验组以2.5 g/kg·BW·d剂量菜籽多肽灌胃ICR小鼠,对照组灌胃等体积蒸馏水,14 d后进行直接睡眠试验、戊巴比妥钠阈下剂量催眠试验、巴比妥钠睡眠潜伏期试验和延长戊巴比妥钠睡眠时间试验,同时记录小鼠体重和脏器指数用于观察小鼠及其脏器健康程度。结果表明:菜籽多肽有显著提高小鼠睡眠率(Ρ<0.05)和显著延长睡眠时间(Ρ<0.05)的作用,但没有缩短小鼠睡眠潜伏期的作用(Ρ>0.05)。试验期间2组小鼠体重和脏器指数均没有差异。说明菜籽多肽可通过延长小鼠睡眠时间来改善睡眠。
The effect of rapeseed peptides on improving mice slumber were studied. Mice in test group were gavaged rapeseed peptides with dose of 2.5 g/kg·BW·d, while control group gavaged with same volume of distilled water. 14 days later, direct hypnosis experiment, subthreshold dose of pentobarbital sodium hypnotic experiment, barbital sodium sleep latency experiment and prolonged pentobarbital sodium sleep time experiment were conducted. Meanwhile, the body weight and organ index of mice were recorded. The result indicated that rapeseed peptides could significantly improve mice sleep rate （P〈0.05） and significantly prolong the sleeping time of mice （ P〈0.05 ）. However rapeseed polypeptides did not have the effect of shortening sleep latency time. During the experiment period, the body weight and organ index had no significant difference between control group and test group. The results showed that rapeseed peptides had effect of improving slumber through prolonging sleeping time.
出处
《粮食与油脂》
北大核心
2017年第4期57-60,共4页
Cereals & Oils
基金
江苏省科技成果转化专项资金(BA2008100)
江苏大学高级人才科研启动基金(16JDG049)
关键词
菜籽
多肽
改善睡眠
rapeseed
peptides
improve slumber
