摘要
目的分析1例男性肝硬化患者服用螺内酯后出现乳房发育的不良反应,探索可能原因,提高药学服务水平。方法临床药师结合患者的基础疾病、用药史等诊疗经过,查找国内外相关文献,对不良反应产生原因进行分析。结果患者停用螺内酯后,乳房疼痛减轻至消失,推测螺内酯是导致患者乳房发育的可疑药物。结论临床药师通过关注药品不良反应,可以为临床提供药物信息和更好的药学服务。
Objective To study one male patient with cirrhosis for spironolactone induced gynecomastia and promote clinical pharmacists providing better pharmaceutical cares. Methods Based on the patient＇s diseases and medication history, clinical pharmacists searched related literature and analyzed the cause of gyneeomastia for the patient. Results The patient＇s breast pain was relieved and finally disappeared after termination of spironolactone. Therefore, spironolactone was suspected to be the drug to cause gynecomastia. Conclusion Clinical pharmacists can improve pharmaceutical cares by carefully monitoring the adverse reactions and selecting appropriate medications.
作者
孙钟慧
王铀
段海洁
谭月桂
梁乐
姚鸿萍
SUN Zhonghui WANG You DUAN Haijie TAN Yuegui LIANG Le YAO Hongping(Department of Pharmacy, First Hospital Affiliated to Xi＇an Jiaotong University, Xi＇an 710061, China Department of Pharmacy, No. 5 Hospital of Xi＇ an City, Xi＇an 710082,China Department of Pharmacy, No. 1 Hospital of Xi＇an City, Xi＇an 710002,China)
出处
《药学实践杂志》
CAS
2017年第2期165-166,170,共3页
Journal of Pharmaceutical Practice
关键词
螺内酯
肝硬化
乳房发育
药品不良反应
spironolactone
cirrhosis
gynecomastia
adverse drug reactions
