摘要感染是导致新生儿死亡的重要原因。新生儿严重感染可以感染性休克起病或进行性加重发展为感染性休克,在起病开始即可表现为心血管功能不全,需要液体复苏或血管活性药物治疗。如感染进程不能终止,则发展为多器官功能障碍综合征（multiple organ dysfunction syndrome,MODS）,甚至死亡。
1Rais-Bahrami K, Van Meurs KE Venoarterial versus venovenous ECMO for neonatal respiratory failure[J]. Semin Perinatol, 2014,38(2):71-77. DOI: 10.1053/j.semperi.2013. 11.003.
2Bartlett RH, Harken DE. Instrumentation for cardiopulmonary bypass--past, present, and future[J]. Med Instrum, 1976,10(2): 119-114.
4Jung C, Janssen K, Kaluza M, et al. Outcome predictors in cardiopulmonary resuscitation facilitated by extracorporeal membrane oxygenation[J]. Clin Res Cardiol, 2016,105(3):196- 205. DOI: 10.1007/s00392-015-0906-4.
5Zhao J, Liu J, Feng Z, et al. Clinical outcomes and experience of 20 pediatric patients treated with extracorporeal membrane oxygenation in Fuwai Hospital[J]. ASAIO J, 2008,54(3):302- 305. DOI: 10.1097/MAT.0b013e318172b445.
6Shi J, Chen Q, Yu W, et al. Continuous renal replacement therapy reduces the systemic and pulmonary inflammation induced by venovenous extracorporeal membrane oxygenation in a porcine model[J]. Artif Organs, 2014,38(3):215-223. DOI: 10.1111/aor. 12154.
7Lou S, MacLaren G, Paul E, et al. Hemofiltration is not associated with increased mortality in children receiving extracorporeal membrane oxygenation[J]. Pediatr Crit Care Med, 2015,16(2):161-166. DOI: 10.1097/PCC. 0000000000000290.
8Lou S, MacLaren G, Best D, et al. Hemolysis in pediatric patients receiving centrifugal-pump extracorporeal membrane oxygenation: prevalence, risk factors, and outcomes[J]. Crit Care Med, 2014,42(5):1213-1220. DOI: 10.1097/CCM. 0000000000000128.
