摘要
目的系统评价早期循序渐进运动(early progressive exercise,EPE)对ICU获得性衰弱的影响。方法检索The Cochrane Library、The Joanna Briggs Institute Library(JBI)、Pub Med、MEDLINE、EMBASE、CINAHL、中国生物医学文献数据库、中国知网及万方数据库中关于EPE对ICU获得性衰弱影响的随机对照试验。经筛选文献,提取资料与评价文献质量后,采用Rev Man 5.3软件行Meta分析。结果最终纳入11项随机对照试验,1378例患者。经Meta分析,EPE能有效提高患者的医学研究理事会评分[Z=6.19,95%CI(4.15,8.00),P<0.001],改善患者的独立功能状态[Z=2.48,95%CI(1.45,23.88),P=0.01],但EPE在增强患者肌力强度、最大吸气压力方面并未显示明显优势,合并效应无统计学意义(P>0.05)。结论 EPE可有效改善ICU机械通气患者独立功能状态,但在预防ICU获得性衰弱方面并未显示出优势,尚需开展深入研究进行验证。
Objective To evaluate the effects of early progressive exercise （EPE） on ICU acquired weakness（ICU- AW）. Methods A computerized search was performed through The Cochrane Library,The Joanna Briggs Institute Library （JBI）,PubMed,MEDLINE,EMBASE,CINAHL,CBM,CNKI and Wanfang Database for randomized controlled trials （RCTs） which studied the effects of EPE on ICU-AW. The recta-analysis was performed after searching databases,extracting data and assessing quality of included studies using RevMan 5.3. Results Totally 11 RCTs which included 1378 participants were incorporated into the recta-analysis. The meta-analysis results well suggested that EPE effectively increased Medical Research Council score（MRC-score） [Z=6.19,95%CI（4.15-8.00）,P〈0.001 ], improved the patient＇s independent living functional status [Z=2.48,95% CI（ 1.45-23.88 ）,P=0.01]. While it failed to support the effectiveness on improving muscle strength and maximal inspiratory pressure（P〉0.05）. Conclusion EPE is effective to improve the independent living function of ICU patients with mechanical ventilation. While it cannot effectively prevent ICU-AW. It is necessary to carry out high quality researches to confirm the results.
出处
《中华护理杂志》
CSCD
北大核心
2017年第2期177-181,共5页
Chinese Journal of Nursing
基金
泰山医学院教育教学研究课题(XY2015084)
关键词
运动训练
重症监护病房
获得性衰弱
META分析
Early Progressive Exercise
Intensive Care Units
Acquired Weakness
Meta-Analysis
