摘要
目的探讨肾活检用于慢性肾脏病急性肾衰竭患者中的诊断效果。方法选取本院2010年1月-2016年1月接诊的慢性肾脏病急性肾衰竭患者50例,分别对其进行肾活检及血清胱抑素C检测,比较两种方法的诊断结果,并分析患者的临床诊治及转归情况。结果肾活检对急性肾衰竭的检出率为100%,血清胱抑素C检测肾衰竭的检出率为82%,差异有统计学意义（P〈0.05）。50例患者经过肾活检检查后,对原有的诊断进行修正,同时改变了原来的治疗方案,积极治疗的原发病的同时,将病因去除,其中38例患者的肾功能恢复基础水平,9例患者血肌酐水平下降超过15%,2例患者肾功能无变化,1例患者进行维持性透析。结论血清胱抑素C检测可作为早期筛查急性肾衰竭的重要指标,对于慢性肾脏病急性肾衰竭诊断困难的患者,可采用肾活检进行诊断,其创伤小、操作简单,易被患者接受,可明确肾脏疾病病理类型,为治疗方案的制定提供可靠的依据,使患者尽早的接受治疗,恢复肾功能,改善生活质量。
Objective To investigate diagnosis effect analysis of renal biopsy in chronic kidney disease patients with acute renal failure. Methods 50 cases of chronic kidney disease patients with acute renal failure cured in our hospital from January 2010 to January 2016 were selected. Renal biopsy and serum cystatin C detection were respectively used to compare the diagnostic results of the two methods. The clinical diagnosis and prognosis of the situation of the patients were analyzed. Results The detection rate of renal biopsy in patients with acute renal failure was 100%, the detection rate of serum cystatin C in renal failure was 82%, and the differences were statistically significant（P〈0.05）. After renal biopsy examination, the original diagnoses of 50 patients were updated, changed the original treatment regimen, and removed the causes at the same time active treatment of primary disease. Among them, 38 cases were recovered to the basic level of renal function, 9 cases serum creatinine levels decreased by more than 15%, 2 patients had no change of renal function, 1 case needed maintenance dialysis. Conclusion Detection of serum cystatin C can be used as an important index for early screening of acute renal failure. Renal biopsy can be used in the diagnosis of chronic kidney disease in patients with acute renal failure. The wound is small. The operation is simple. It is easy to be accepted by patients. It can be clearly pathological types of kidney disease. It can provide a reliable basis for the formulation of the treatment plan. It can enable patients to receive treatment as early as possible, restore renal function, and improve the quality of life.
出处
《中国医药科学》
2016年第19期186-188,208,共4页
China Medicine And Pharmacy
关键词
肾活检
慢性肾脏病
急性肾衰竭
尿毒症
Renal biopsy
Chronic kidney disease
Acute renal failure
Uremia
