摘要
目的:研究早期肠内营养添加谷氨酰胺对昏迷儿童营养和免疫功能的影响。方法:将符合入选条件的昏迷儿童根据肠内营养分为添加谷氨酰胺组(GEN组)和未添加谷氨酰胺组(EEN组),比较2组患儿治疗前、治疗后体质量指数、PA、ALB、TP、IgG、IgA、IgM、CD3^+、CD4^+和CD8^+的差异。结果:GEN组和EEN组昏迷患儿治疗前体质量指数、PA、ALB、TP、IgG、IgA、IgM、CD3^+、CD4^+和CD8^+均无明显差异,EEN组昏迷患儿治疗后的体质量指数、PA、ALB、TP、IgG、IgA、IgM、CD3^+、CD4^+和CD8^+较治疗前无明显改变;GEN组昏迷患儿治疗后的PA、ALB、TP、IgG、IgA、IgM、CD3^+、CD4^+和CD8^+较治疗前均显著增加(均P<0.05),且均显著高于EEN组昏迷患儿(均P<0.05)。结论:早期肠内营养添加谷氨酰胺可显著提高昏迷儿童营养状况及免疫功能,其疗效显著高于单纯肠内营养。
Objective:To study the effects of early enteral nutrition with glutamine supplement on nutrition status and immune function in coma children.Method:Coma children were divided into GEN group and EEN group according their feeding methods.BMI,PA,ALB,TP,IgG,IgA,IgM,CD3+,CD4+and CD8+were detected and compared in two groups.Result:There were no significant difference in BMI,PA,ALB,TP,IgG,IgA,IgM,CD3+,CD4+and CD8+between two groups before the treatment.After the therapy,PA,ALB,TP,IgG,IgA,IgM,CD3+,CD4+and CD8+in GEN group were significantly higher than those in EEN group(P〈0.05).Conclusion:Glutamine supplement in early enteral nutrition could significantly improve nutrition status and immune function in coma children.
出处
《临床急诊杂志》
CAS
2016年第9期679-681,共3页
Journal of Clinical Emergency
关键词
早期肠内营养
谷氨酰胺
昏迷儿童
营养
免疫功能
early enteral nutrition
glutamine
coma children
Glutamine
nutrition status
immune function