摘要
目的评估创伤性脑损伤患者发生创伤性脑梗死（PTCI）的危险因素及其预后。方法选取408例创伤性脑损伤（TBI）患者，其中PTCI 28例，采用单因素分析发生PTCI的可能因素，采用多因素分析发生PTCI的危险因素。结果408例患者中，28例（6.9%）发生PTCI，单因素分析表明，发生PTCI的危险因素是低血压、颅内感染、脑损伤类型、初始GCS评分、止血药使用（P均〈0.05）；多因素分析表明，初始低GCS评分、脑疝形成、脑挫裂伤、低血压状态是PTCI发生的独立相关因素（P均〈0.05）；PTCI导致患者重残（78.6%比28.4%，P〈0.01）与死亡（10.7%比2.4%，P＝0.012）发生率高于非PTCI患者，差异有统计学意义。结论脑挫裂伤、低血压状态、初始低GCS评分、脑疝形成是创伤性脑损伤患者发生创伤性脑梗死的危险因素，PTCI提示患者预后不良。
ObjectiveTo evaluate the outcome and risk factors of patients with traumatic brain injury（TBI） occurred post-traumatic cerebral infarction（PTCI）.MethodsFour hundred and eight patients with TBI were selected, including 28 PTCI patients. The clinical data were retrospectively analyzed. Single factor analysis was used to analyzed the possible factors of PTCI, Multivariate analysis was used to analyzed the risk factors of PTCI.ResultsTwenty-eight cases（6.9%） had PTCI. Univariate analysis showed that the risk factors of PTCI were hypotension, intracranial infection, type of brain injury, initial GCS score and the use of hemostatic agents（P〈0.05）. Multivariate logistic regression analysis showed that low initial GCS score, herniation, brain contusion, and hypotension was independently associated with the occurrence of PTCI （all P〈0.05）. PTCI patients with severe disability （78.6% vs. 28.4%, P〈0.01） and mortality （10.7% vs. 2.4%, P=0.012） were significantly higher than than those in non PTCI patients.ConclusionsThe low initial GCS score, herniation, brain contusion, hypotension are risk factors for TBI patients occurred PTCI, PTCI prompted poor prognosis.
作者
孙学强
潘姗姗
纪德峰
潘静坤
Sun Xueqiang Pan Shanshan Ji Defeng Pan Jingkun(Department of Traumatology, Jiaozhou People＇ s Hospital, Jiaozhou 266300, Chin)
出处
《中国实用医刊》
2017年第1期38-40,共3页
Chinese Journal of Practical Medicine
关键词
创伤性脑损伤
脑梗死
危险因素
Traumatic brain injury
Cerebral infarction
Risk factors
