摘要
为了解血清总胆汁酸 (TBA)水平与肝实质病变的关系。对 10 2例慢性肝炎患者作肝活检 ,观察肝组织分级纤维化分期 ,并检测血清TBA、常规肝功白蛋白 (Alb)、总胆红素 (TBil)、谷丙转氨酶 (ALT)。肝组织炎症轻度(G1-2 ,S0 -2 )、中度 (G3 ,S1-3 )、重度 (G4S4)的TBA水平 (x±s)分别在 (16 74± 13 34) μmol/L、(72 2 5± 6 8 4 9)μmol/L和 (186 34± 96 18) μmol/L ,呈重度 >中度 >轻度状态。轻度组与中度组及中度与重度组比较均为P <0 0 1。慢性肝炎血清TBA水平与肝组织炎症程度具有良好正比关系。对估计肝实质病变程度具有重要临床价值。
To find out the relationship between the level of serum TBA of chronic hepatitis and the degree of hepatic inflammation. A careful observation was made on secrection and differentiation period of hepatic inflammation, and Alb, TBil and ALT in the biopsies of liver done from 102 patients with chronic hepatitis. The level of serum TBA (x±s) on slightness (G 1-2 ,S 0-2 ), medium (G 3,S 1-3 ) and severity (G 4,S 4)of hepatic inflammtion were 16 74±13 34(μmol/L),72 25±68 94(μmol/L), and 186 34±96 18(μmol/L), being severity>medium>slightness. Both the comparisions between slightness medium, and medium and severity showed P <0 01. These result suggest that the level of serum TBA of chronic hepatitis is in direct proportion to the degree of hepatic inflammtion, which has significant value in the diagnosis for evaluation of the degree of hepatic inflammation.
出处
《临床肝胆病杂志》
CAS
北大核心
2002年第4期211-212,共2页
Journal of Clinical Hepatology
