摘要
目的：探讨二丁酰环磷腺苷钙与红花黄色素联合治疗冠心病的疗效和安全性。方法选取西宁海湖医院2015年6月至2016年6月收治的冠心病患者100例，完全随机分为对照组和观察组，每组50例。两组基础治疗均为应用注射用二丁酰环磷腺苷钙40 mg加入5%葡萄糖注射液500 ml中，1次/d，静脉滴注，观察组在对照组基础上加用注射用红花黄色素100 mg加入0.9%的氯化钠注射液中，1次/d，静脉滴注。两组均连续用药15 d，观察治疗前后的临床症状、心电图、凝血四项、血脂的变化、综合评估总有效率、不良反应发生率。结果观察组和对照组的临床症状、心电图、凝血四项和血脂均有显著改变，观察组的总有效率为90%明显优于对照组的60%，差异有统计学意义（P〈0.05）。结论注射用二丁酰环磷腺苷钙联合注射用红花黄色素治疗冠心病疗效较好，不良反应发生率低。
ObjectiveAnalyze the effect and safety of calcium dibutyryladenosine cyclophosphate for injection and saffower yellower for injection in treating coronary heart disease.MethodsA total of 100 patients with coronary heart disease from June 2015 to June 2016 were randomly divided into control group and observasion group in Xining Haihu Hospital, 50 cases in each group. Both foundation treatments are calcium dibutyryladenosine cyclophosphate for injection 40mg, in 500 ml 5% glucose injection, every day one time. Saffower yellower for ynjection 100 mg, in 250 ml 0.9% sodium chloride injection, every day one time, was additionally given in observation group. The treatment was lasted for 15 days. Observation changes in the two groups for the clinical symptoms, electrocardiogram, blood coagulation four, blood lipid, through beginning and ending in treatment.Results The clinical symptoms, ECG, blood coagulation and blood lipid in the observation group and control group were significantly changed, the total effective rate of the observation group was 90%, which significantly better than that of the control group, the difference was statistically significant （P〈0.05）.Conclusion Treatment of coronary heart disease with the combination of calcium dibutyryladenosine cyclophosphate for Injection and saffower yellower for injection is better. Low incidence of adverse reaction.
出处
《中国临床实用医学》
2016年第6期33-36,共4页
China Clinical Practical Medicine
关键词
注射用二丁酰环磷腺苷钙
注射用红花黄色素
冠心病
心电图
Calcium dibutyryladenosine cyclophosphate for injection
Saffower yellower for injection
Coronary heart disease
Electrocardiogram
