摘要
目的探究单纯肿瘤摘除与部分胰腺切除2种不同手术方式对治疗胰岛素瘤的生存情况。方法回顾性研究2003年5月至2015年8月期间收治的99例胰岛素瘤手术患者的临床资料．使用SPSS21．0统计软件对所采集的数据进行分析。结果单纯肿瘤摘除术组的平均生存时间为103．3个月，高于部分胰腺切除术组的77．5个月，差异具有统计学意义（P=-0．006）。2种不同手术方式术后大部分长、短期并发症发生率差异无统计学意义（P〉0．05），但新发糖尿病的发生率比较差异具有统计学意义（P=0．004）。结论治疗大小合适的胰岛素瘤的手术治疗应首选单纯肿瘤摘除的方式，该方式对患者术后的生存情况更佳。
Objective To compare the survival conditions of patients with insulinoma after enucleation of insulinoma or partial resection of pancreas. Methods The clinical data of 99 patients with insulinoma, treated with surgery from May. 2003 to Aug. 2015 were retrospectively analyzed. Of the 99 patients, 38 received enucleation of insulinoma alone and 61 received partial resection of pancreas. The overall data were analyzed by SPSS 21.0 software. Results Average survival of patients after enucleation of insulinoma （103.3 months） was longer than that of patients after partial resection of pancreas（77.5 months）, and the difference had statistical significance （P=0.006）. The difference of the incidence of most chronic or temporary complications had no statistical significance between the two groups （P〉0.05）, except for new-onset diabetes （P=0.004）. Conclusion Enucleation of insulinoma should be firstly recommended for patients with insulinoma in suitable size, which can provide patients with better survival condition.
作者
刘力笼
杨敏
王幸
张伟坚
刘续宝
Liu Lilong Yang Min Wang Xing Zhang Weijian Liu Xubao(Department of Pancreatic Surgery, West China Hosp ital of Sichuan University, Chengdu 610041, China West China Medical School of Sichuan University, Chengdu 610041, China)
出处
《中华内分泌外科杂志》
CAS
2016年第6期461-464,共4页
Chinese Journal of Endocrine Surgery
关键词
胰岛素瘤
手术方式
生存分析
Insulinoma
Surgical procedures
Survival analysis
