摘要
目的:探讨物理治疗结合药物治疗对持续性变应性鼻炎(allergic rhinitis,AR)的疗效。方法:将192例患者随机分为3组,A组72例,B组70例,C组50例,AB组分别在鼻内镜下行聚焦超声与射频消融治疗,术后应用糠酸莫米松鼻喷雾剂喷鼻1个月,C组应用糠酸莫米松鼻喷雾剂+西替利嗪片1个月。治疗后随访6个月,用计分法进行疗效评价。结果:总有效率分别为1个月:A组97.2%,B组97.1%,C组96.0%;6个月:A组90.3%,B组87.1%,C组64.0%。3组治疗后1个月症状评分比较,疗效相当,无统计学意义(P>0.05);3组患者治疗后6个月有效率比较,差异具有显著的统计学意义,A组与B组有效率均高于C组(P<0.05);治疗后喷嚏症状评分比较,A组优于B组,差异有显著性(P<0.05),但鼻塞评分比较,B组优于A组,差异有显著性(P<0.05)。结论:两种物理治疗方法联合糠酸莫米松治疗持续性AR,前者改善喷嚏症状优于后者,但改善鼻塞症状不如后者。药物治疗持续性AR的远期疗效不及物理治疗联合药物治疗。聚焦超声联合糠酸莫米松治持续性AR,值得推广,尤其适合中-重度持续性AR患者。
Objective：To investigate the therapeutic effects of physical therapy and pharmacotherapy in the treatment of persistent allergic rhinitis. Methods： 192 patients were randomly divided into 3 groups, A group 72 cases, B group 70 cases. A and B group were treated with focused ultrasound and radiofrequency ablation respectively under the endoscope and using spraying Mometasone Furoate Nasal Spray for 1 month after the operation. Patients of C group use the Mometasone Furoate Nasal Spray and Cetirizine Hydrochloride Tablets for 1 month. Follow up for 6 months after treatment and evaluate the curative effect with scoring method. Results：Total effectiveness was as followed：lst months：A group 97.2%, B group 97. 1% C group 96.0% ;6 months： A group 90.3%, B group 87. 1% ,C group 64. 0%. The curative effect score of three group after the treatment for 1 month have no significant difference （ P 〉 0.05 ）. Comparing the efficiency of patients in three groups after treatment for 6 months, there was significant difference of statisti- cally significance. The efficiency of A and B group were higher than group C （ P 〈 0.05）. A group was better than B group with the score of sneezing after the treatment,the difference was significant （ P 〈 0.05）. But B group was better than A group with the score of nasal congestion, the difference was significant （ P 〈 0.05 ）. Conclusion： The curative effect of treatment with two physical therapy methods combined with mometasone furoate for persistent allergic rhinitis,the former is better than the latter for sneezing,but the improvement of nasal congestion is less than the latter. Long-erm therapeutic effect of drug with AR is less than physical therapy in combination with drug. The treatment with focused ultrasound combined with mometasone furoate for persistent AR is worth promoting, especially suitable for medium and severe persistent AR patients.
出处
《川北医学院学报》
CAS
2016年第6期820-823,共4页
Journal of North Sichuan Medical College
基金
四川省教育厅基金资助(13ZB0241)
川北医学院博士科研启动基金(CBY13-QD-08)
南充市科学技术和知识产权局(16YFZJ0021)
关键词
鼻炎
变应性
持续性
物理治疗
药物治疗
Rhinitis
Allergic
Persistent
Physical therapy
Pharmacotherapy
