摘要
目的探讨血浆D二聚体在卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS)患者治疗中的改变,为临床治疗提供指导意义。方法回顾性分析安徽省立医院生殖医学中心75例体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)后因OHSS住院治疗患者的临床资料,分析患者治疗前、后血浆D二聚体的差异。结果75例中重度OHSS患者经积极纠正血液浓缩、纠正低蛋白血症、预防血栓形成治疗后,在入院日D二聚体、出院日D二聚体的差异有统计学意义(P<0.05)。结论动态检测OHSS患者治疗过程中血浆D二聚体的变化,对评估其临床治疗及判断预后有指导意义。
Objective To investigate the change of plasma D-dimers during the treatment of patients with ovarian hyperstimulation syndrome,and to discuss the clinical significance of monitoring D-dimer levels.Methods The clinical data of75 inpatients were analyzed retrospectively（from July2015 to June2016） who suffered from OHSS following IVF-ET. Paired T tests were used to reveal the D-dimer level of patients before and after treatment.Results A statistical significance of plasma D-dimer levels was noted between the patients with OHSS on admission and those discharged from hospital（P〈0.05）.Conclusion Monitoring the D-dimer level of patients with OHSS during the treatment,is of significance in evaluation of treatments and prognosis.
出处
《临床输血与检验》
CAS
2016年第6期574-576,共3页
Journal of Clinical Transfusion and Laboratory Medicine
基金
国家自然科学基金青年项目(No.81601244)资助
