摘要
目的探讨辅助生殖技术中中重度卵巢过度刺激综合征(OHSS)的临床特点。方法回顾性分析重庆市妇幼保健院生殖中心2012年6月至2013年4月行体外受精-胚胎移植(包括卵母细胞内单精子显微注射)后出现中重度OHSS并住院治疗的179例患者,对其临床资料进行回顾性分析。根据临床表现分为中度OHSS组和重度OHSS组,以及早发型OHSS组和晚发型OHSS组。结果中重度OHSS患者的年龄、取卵数、入院时转氨酶值、纤维蛋白原正常人数比例差异均无统计学意义(P>0.05),而住院天数、入院时HCT、清蛋白值、入院后转氨酶最高值、清蛋白用量、放腹腔积液患者比例、妊娠率差异均有统计学意义(P<0.05);早发型OHSS患者和晚发型OHSS患者的年龄、入院时转氨酶值、纤维蛋白原正常人数比例差异均无统计学意义(P>0.05),而取卵数、中度OHSS患者比例、住院天数、入院时HCT值、清蛋白值、入院后转氨酶最高值、清蛋白用量、放腹腔积液患者比例、妊娠率差异均有统计学意义(P<0.05)。结论综合OHSS患者的各项血液指标等可以对患者的病情进行评估、治疗和预防;晚发型OHSS患者病情可能更严重。
Objective To investigate clinical characteristics of moderate and severe ovarian hyperstimulation syndrome （OHSS） in assisted reproductive technique .Methods The clinical data of 179 cases with moderate and severe OHSS receiving in vitro fertili‐zation‐embryo transfer （including ICSI） in the hospital from June 2012 to April 2013 were analyzed retrospectively .According to the clinical characteristic ,the OHSS was classified as as the moderate type and severe type ,and the late type and early type . Results It was no statistics difference between moderate type and severe type in the patients age ,number of retrieved oocytes ,ad‐mission transaminase ,proportion of fibrinogen normal numbers（P〉 0 .05） .But it was a statistics difference between moderate type and severe type in the occurring time days of hospitalization ,hematocrit on admission ,albumin value ,transaminase maximum ,albu‐min dosage used ,proportion of paracentesis number ,pregnancy rate（P 〈 0 .05） .It was no statistics difference between early type and late type in the patients age ,admission transaminase ,proportion of fibrinogen normal numbers（P〉 0 .05） .But it was a statistics difference between early type and late type in the number of retrieved oocytes ,the proportion of moderate OHSS patients ,days of hospitalization ,hematocrit on admission ,albumin value ,transaminase maximum ,albumin dosage used ,proportion of paracentesis number ,pregnancy rate（P〈 0 .05） .Conclusion Synthesizing OHSS patients′ blood indexes ,we can evaluated patients′ pathogenet‐ic condition ,the treatment of disease ,and took appropriate preventive measures as soon as possible .Patients with late type may be have more severe pathogenetic condition than patients with early type .
出处
《重庆医学》
CAS
CSCD
北大核心
2014年第31期4219-4221,4224,共4页
Chongqing medicine
