摘要
最近十几年,多种类型的干细胞,包括胚胎干细胞、诱导多能干细胞、骨骼肌干细胞、心脏干细胞和骨髓来源的干祖细胞等,可用于缺血性心脏病诱导的损伤修复和再生医学中,并且逐渐显示出广阔的发展前景。在此本文将介绍几种不同来源的干细胞在治疗缺血性心脏病中的研究概况,为进一步的基础研究和临床试验提供参考。
Over the past decades, multiple types of stem cells, including embryonic stem cells(ESCs), induced pluripotent stem ceils (iPSCs) , skeletal myoblasts, bone marrow-derived stem/progenitor cells and cardiac stem cells (CSCs) , have been found to contribute to the repairment of damage caused by ischemic heart disease (IHD). Stem cell therapy has showed broad prospects for the development of regenerative medicine. In order to provide references for further basic research and clinical trials, this review introduces the studies of stem cells from different sources in the treatment of IHD.
作者
蒋璐璐
杨娜娜
王大新
秦树存
JIANG Lu-Lu YANG Na-Na WANG Da-Xin QIN Shu-Cun(Department of Cardiovascular Medicine, Second Xiangya Hospital of Central South University, Changsha 410011, China Institute of Atherosclerosis, Key Laboratory of Atherosclerosis in Universities of Shandong, Taishan Medical University, Taian 271000,Shandong, China Department of Cardiovascular Medicine, Northern Jiangsu People' s Hospital, Yangzhou 225001, Jiangsu, China)
出处
《中国生物化学与分子生物学报》
CAS
CSCD
北大核心
2016年第11期1206-1212,共7页
Chinese Journal of Biochemistry and Molecular Biology
基金
国家自然科学基金项目(No.30971098)
山东省自然科学基金项目(No.2012ZRB14125)
山东省教育厅科技计划(No.J14LK03)
江苏省“333工程”二层次项目(No.BRA2015171)~~
关键词
干祖细胞
缺血性心脏病
stem/progenitor cells
ischemic heart disease(IHD)