摘要
目的探讨胸腔热灌注化疗治疗恶性胸腔积液的临床效果及可行性。方法选取临床确诊的66例恶性胸腔积液患者,数字随机分为观察组及对照组,每组33例。观察组胸腔热灌注化疗（治疗温度42-43℃）。对照组给与同等剂量化疗药常温关注,对症治疗等措施同观察组。两组治疗均为每周1次,治疗4周后对两组临床疗效、不良反应发生情况。结果观察组总有效率81.81%明显高于对照组69.70%（P〈0.05）,两组均不良反应发生率无统计学意义。结论胸腔内热灌注化疗治疗恶性胸腔积液近期疗效确切,且不良反应较轻,是安全有效的,值得推广与使用。
Objective ：To investigate the clinical effect and feasibility of pleural effusion in the treatment of malignant pleural effusion. Methods ： 66 cases of malignant pleural effusion were randomly divided into observation group and control group, 33 casesin eachgroup. Observation group of thoracic cavity perfusion chemotherapy （treatment temperature 42 - 43 degrees C）. The control group was given the same dose of chemotherapy drugs at room temperature attention, symptomatic treatment and other measures with theobservation group. The two groups weretreated 1 times a week, 4 weeks after the treatment of two groups of clinical efficacy, adverse reactions occurred. Results ： the total effective rate of the observation group was 81. $1% higher than that of the control group 69.70% （ P 〈 0. 05 ）, and the incidence of adverse reactions in the two groups was not statistically significant. Conclusion ： Intrathoracic hyperthermic perfusion chemotherapy in treatment of malignant pleural effusion by short-term efficacy and adverse reactions of lighter, is safeand effective, worthy of promotion and Application
出处
《泰山医学院学报》
CAS
2016年第8期868-869,共2页
Journal of Taishan Medical College
关键词
恶性胸腔积液
胸腔热灌注
腔内化疗
malignant pleural effusion
pleural cavity perfusion
chemotherapy
