摘要
目的:主要研究米非司酮治疗顽固性功能性子宫出血的临床效果并分析。方法:本次的研究对象为2012年7月至2014年6月期间医院收治的124例顽固性功能性子宫出血的患者,将所有患者随机分为两组,每组各有患者62例,命名为实验组和对照组,其中对照组的62例患者给予安宫黄体酮口服进行治疗,实验组的62例患者采用米非司酮口服进行治疗,经过一段时间的治疗后,观察并比较两组患者的治疗效果。结果:两组患者在治疗一段时间后,实验组患者的治疗总有效率明显高于对照组患者的治疗总有效率,两组患者在治疗总有效率上存在明显的差异性(P<0.05);实验组患者在治疗过程中,有2例(3.23%)患者出现不良反应,对照组患者有10例(16.13%)患者出现不良反应,两组患者在不良反应发生率方面有明显的差异性(P<0.05);治疗结束后,实验组患者的复发率为6.45%(4/62)明显低于对照组患者的复发率24.19%(15/62),存在明显的差异性(P<0.05)。结论:采用米非司酮治疗顽固性功能性子宫的治疗效果很明显,不良反应少,复发率低,值得在临床上推广应用。
Objectives： To study and analyze the effect of mifepristone in treating refractory dysfunctional uterine bleeding. Methods： 124 dysfunctional uterine bleeding refractory patients in our hospital from July 2012 to June 2014 were randomly divided into two groups,each of 62 patients. The control group received oral medroxyprogesterone acetate,while the experimental group was treated with oral mifepristone. The treatment effect was compared after a period of treatment. Results： After a period of treatment,the total efficiency of treatment in experimental group was significantly higher than the control group,with statistically significant difference（ P〈 0. 05）.There were 2 cases of adverse reactions in experimental group（ 3. 23%） and 10 cases in control group（ 16. 13%）,with statistically significant difference（ P〈 0. 05）. After treatment,the recurrence rate of experimental group was6. 45%（ 4 /62）,significantly lower than the control group of 24. 19%（ 15 /62）,with statistically significant difference（ P〈 0. 05）. Conclusion： Mifepristone is effective in treating refractory dysfunctional uterine bleeding,with fewer adverse reactions and low recurrence rate,which is worthy of clinical application.
出处
《中国性科学》
2016年第10期44-46,共3页
Chinese Journal of Human Sexuality
关键词
米非司酮
子宫出血
效果分析
Mifepristone
Uterine bleeding
Effectiveness analysis
