摘要
目的比较静脉注射普罗帕酮与胺碘酮治疗阵发性室上性心动过速(PSVT)的临床疗效及安全性。方法将本院2009年1月～2012年1月急诊及住院的PSVT患者86例,随机分为普罗帕酮组45例和胺碘酮组41例,分别给予普罗帕酮、胺碘酮静脉注射治疗,比较两组用药前后转复时间、转复有效率及不良反应率。结果普罗帕酮组转复时间为(8.14±1.80)min,胺碘酮组为(19.31±2.95)min,两组比较差异有统计学意义(t=21.58,P<0.05);两组转复率分别为84.44%(38/45)、85.37%(35/41),差异无统计学意义(χ2=0.12,P>0.05);两组不良反应发生率差异无统计学意义(22.22%vs21.95%,χ2=0.01,P>0.05)。结论静脉注射普罗帕酮与胺碘酮治疗阵发性室上性心动过速安全、有效,均可作为治疗PSVT的一线药物。
Objective To explore the effect and safety of intravenous Propafenone and Amiodarone treatment on paroxysmal supraventricular tachycardia（PSVT）.Methods Eighty-six patients of PSVT who were admitted our hospital from January 2009 to January 2012 were randomly divided into two groups,intravenous Propafenone group（n = 45） and intravenous Amiodarone group（n = 41）.Comparition of the termination rate and adverse events rate were observed between the two groups.Results The time of heart beat recovery in Propafenone group were（8.14±1.80） min and Amiodarone group were（19.31±2.95） min,there had difference of statistical significance between the two groups（t = 21.58,P 0.05）.The termination rate of PSVT was 84.44%（38/45）in Propafenone group and 85.37%（35/41） in Amiodarone group,showed no significant difference（χ2=0.12,P 0.05）.The incidence rates of side effect were respectively without significant difference（22.22% vs 21.95%,χ2=0.01,P 0.05）.Conclusion Intravenous Propafenone and Amiodarone treatment on clonic paroxysmal supraventricular tachycardia is safe,effective and can be used as a drug treatment PSVT line.
出处
《中国当代医药》
2012年第9期67-68,共2页
China Modern Medicine
