摘要
目的观察、讨论果糖注射液对慢性乙肝合并糖尿病患者血糖的影响。方法选择2014年2月-2015年12月我院收治的62例慢性乙肝合并糖尿病患者进行研究，随机分为两组。观察组32例，采用10％果糖注射液静脉滴注；对照组30例，采用生理盐水静脉滴注。在滴注前、滴注完毕时、滴注完毕后1．5h三个时间段测定两组患者的血糖和胰岛索水平，连续测定3d，观察有无不良反应和其他指标异常。结果两组患者的血糖水平在滴注过程中，观察组由（8．2±2．2）mmol/L上升至（8．4±3．6）mmol／L，对照组由（8．1±1．9）mmol/L上升至（8．2±2．7）mmol／L；滴注完毕后，血糖水平略有下降，保持稳定。两组患者血糖变化比较，差异无统计学意义（P〉0．05）。在滴注过程中，对照组胰岛素水平呈下降趋势，滴注前后差异明显（P〈0．05）；观察组胰岛素水平略有上升，滴注前后无明显差异（P〉0．05）。观察组胰岛素水平稳定性显著优于对照组。结论果糖注射液作为输液溶剂用于慢性肝炎合并糖尿病患者安全、可靠。不会对患者血糖水平造成影响，胰岛素水平稳定性也较好，值得广泛推广应用。
Objective To observe and discuss the effect of fructose on blood sugar in diabetic patients with chronic hepatitis B. Methods Chose 62 patients with chronic hepatitis B patients with diabetes mellitus in our hospital from February 2014 to December 2015 and randomly divided them into observation group and control group. Observation group of 32 patients, with 10% fructose intravenous injection; control group of 30 patients, with intravenous infusion of normal saline. In three time segments, before infusion, when infusion was completed and 1.5 h after infusion completed, glucose and insulin levels of the two groups of patients were measured, continuous determination of 3 d, whether the adverse reactions and other abnormalities were observed. Results During the infusion in the two groups, the blood glucose levels of the observation group was （8.2±2.2） mmol/L, and increased to （8.4±3.6）mmol/L, and the one of the control group was （8.1±1.9） mmool/L, increased to （8.2±2.7） mmol/L; after infusion, blood glucose levels decreased slightly, remained stable. Two changes in blood glucose compared to patients were not statistically significant（P〉0.05）. In the infusion process, the insulin levels of control group decreased significant before and after the infusion （P〈0.05）; the obser vation group had a slight increase in insulin levels, difference was no significant before and after infusion（P〉0.05）. Insulin stability of the observation group was significantly better than the control group. Conclusion Fructose as a solvent for the safety of infusion in patients with diabetes and chronic hepatitis, reliable, does not affect blood glucose level, the insulin level is also stable, is worth widely use.
出处
《中国现代医生》
2016年第25期80-82,共3页
China Modern Doctor
关键词
果糖注射液
慢性乙肝
糖尿病
血糖
Fructose injection
Chronic hepatitis B
Diabetes mellitus
Blood glucose
