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老年2型糖尿病患者七时点血糖与糖化血红蛋白的相关性分析 被引量:4

Correlation analysis between seven-point capillary blood glucose profiles and HbA_(1c) in elderly patients with type 2 diabetes mellitus
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摘要 目的评价老年2型糖尿病患者不同时间点的毛细血管血糖对评估血糖控制的相对价值。方法检测30例老年2型糖尿病患者的7个时点毛细血管血糖(3餐前、3餐后2h和睡前),分析糖化血红蛋白(HbA1c)与血糖的关系。结果对平均血糖和HbA1c进行直线回归分析,平均血糖和7个时点血糖与HbA1c均明显相关(r值分别为0.87及0.50~0.86,均为P<0.01),午餐后2h血糖、晚餐后2h血糖和睡前血糖与HbA1c具有更好的相关性。结论午餐后2h、晚餐后2h及睡前血糖在预测血糖控制方面优于其他时间点的血糖,在评价老年2型糖尿病患者血糖控制时,可作为HbA1c的一个补充指标。 Objective To evaluate the relative value of multiple capillary blood glucose (BG) at different time points to evaluate glucose control in elderly patients with type 2 diabetes mellitus. Methods HbA1c and corresponding seven point capillary blood glucose profiles (premeal, postmeal and bedtime) obtained in thirty elderly patients with type 2 diabetes mellitus were analyzed to define the relationship between HbA1c and BG. Results Linear regression analysis, using mean capillary blood glucose (MBG) and HbA1c, produced a relationship formula of MBG (mmol/L) =1.47× HbA1c, -0. 892,r=0.87. Seven point capillary blood glucose profiles were all significantly correlated with HbA1c. Among individual time points, the BG of postlunch, postdinner and bedtime showed higher correlations with HbA1c, than other time points. Conclusions The BG of postlunch, postdinner and bedtime are better predictors of glycemic control than the BG of prebreakfast, postbreakfast, preluncb and predinner and they be more widely used to supplement for HbA1c in evaluating the glucose control of elderly patients with type 2 diabetes mellitus.
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2005年第10期736-738,共3页 Chinese Journal of Geriatrics
关键词 糖尿病 2型 血糖 血红蛋白A 糖基化 Diabetes mellitus, type 2 Blood glucose Hemoglobin A, glycosylated
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