期刊文献+

Dx-pH检测系统在咽喉反流性疾病中的初步应用 被引量:11

Preliminary application of Dx-pH monitoring system in laryngopharyngeal reflux disease
原文传递
导出
摘要 目的总结分析Dx-pH检测系统在有咽喉反流性疾病临床症状的患者中的初步使用情况及其临床价值。方法回顾性分析2015年2—12月在中日友好医院耳鼻咽喉头颈外科就诊的54例有咽喉反流性疾病症状的患者资料。所有患者均行咽喉pH检测(Dx-pH)、纤维喉镜检查、反流症状指数(reflux symptoms index,RSI)和反流体征量表(reflux finding score,RFS)评分。 结果54例患者中,Ryan指数阳性者26例,阳性率48.2%。Ryan指数阳性主要表现为直立位Ryan指数阳性(24/26例),占Ryan阳性的92.3%。质子泵抑制剂治疗8周后症状未能完全缓解的22例患者中,13例Ryan指数阳性,阳性率59.1%。Ryan指数阳性与RSI和/或RFS量表评分阳性结果不一致(κ=-0.013)。 结论尽管与RSI/RFS评分不一致,但是Dx-pH检测系统能检测出咽喉反流事件,帮助临床医师明确诊断咽喉反流性疾病,减少误诊。 ObjectiveTo summarize the application and significance of Dx-pH monitoring system in laryngopharyngeal reflux disease. MethodsFifty-four patients who had symptoms of laryngopharyngeal reflux disease in our department from February to December in 2015 were retrospectively analyzed in this study. All patients were evaluated with reflux symptoms index(RSI), flexible laryngoscope and reflux finding score(RFS), and larygopharygeal Dx-pH monitoring. ResultsAmong all 54 patients, there were 26 patients whose Ryan score were positive(48.2%). The positive Ryan score mainly emerged when the patients were upright(24/26, 92.3%). Among 22 patients whose symptoms could not alleviate well by 8 weeks proton pump inhibitors treatment, there were 13 patients(59.1%) with positive Ryan scores. The Ryan scores were not in good accordance with RSI and RFS(κ=-0.013). ConclusionsAlthough the results were not in good accordance with RSI/RFS, Dx-pH monitoring system could prove laryngopharyngeal reflux events in patients with laryngopharyngeal reflux disease and help physicians to diagnose.
出处 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2016年第9期666-670,共5页 Chinese Journal of Otorhinolaryngology Head and Neck Surgery
关键词 咽喉反流 PH检测 Laryngopharygeal reflux pH monitoring
  • 相关文献

参考文献14

  • 1Wong RK, Hanson DG, Waring P.I, et al. ENT manifestations of gastroesophageal reflux [ J ]. Am J Gastroenterol, 2000, 95 ( 8 Suppl) : S15-22.
  • 2Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index (RSI)[ J]. J Voice. 2002, 16 (2): 274-277.
  • 3Belafsky PC, Postma GN, Koufman JA. The validity and reliability of the reflux finding score (RFS) [ J ]. Laryngoscope, 2001, 111 ( 8 ) : 1313-1317. DOI: 10. 1097/00005537- 200108000-00001.
  • 4李进让.咽喉反流性疾病诊断与治疗专家共识(2015年)[J].中华耳鼻咽喉头颈外科杂志,2016,51(5):324-326. 被引量:172
  • 5Ayazi S, Lipham JC, Hagen JA, et al. A new technique for measurement of pharyngeal pH: normal values and discriminating pH threshold [J]. J Gastrointest Surg. 2009, 13 ( 8 ) : 1422-1429. DOI: 10. 1007/s11605-009-0915-6.
  • 6Rees C J, Belafsky PC. Lmyngopharyngeal reflux: Current concepts in pathophysiology, diagnosis, and treatment [ J ]. Int J Speech Language pathol, 2008, 10(4): 245-253. DOI: 10. 1080/17549500701862287.
  • 7Babaei A, Bhargava V, and Mittal IRK. Upper esophageal sphincter during transient lower esophageal sphincter relaxation: effects of reflux content and posture[J]. Am J Physiol Gastrointest Liver Physiol. 2010, 298(5) : G601-607. DOI: 10. l152/ajpgi. 00486. 2009.
  • 8Wiener GJ, Tsukashima R, Kelly C, et al. Orophacyngeal pI-I monitoring for the detection of liquid and aerosolized supraesophageal gastric reflux[ J]. J Voice, 2009, 23 (4): 498-504. DOI : 10. 1016/j. jvoice. 2007.2. 005.
  • 9Yuksel ES, Slaughter JC, Mukhtar N, et al. An oropharyngeal pH monitoring device to evaluate patients with chronic laryngitis [J]. Neurogastroenterol Motil, 2013, 25 (5) : e315-323. DO/: 10. 1ll l/nmo. 12109.
  • 10Beaver ME, Karow CM. Clinical utility of 24 hour pharyngeal pH monitoring for hoarseness [J]. J Laryngol and Voice, 2012, 2 (2) : 60453. DOI: 10. 4103/2230-9748. 106979.

二级参考文献29

  • 1Koufman JA. Laryngopharyngeal reflux 2002: a new paradigm of airway disease [ J]. Ear Nose Throat J, 2002, 81 (9 Suppl 2) : 2- 6.
  • 2Cohen JT, Bach KK, Postma GN, et al. Clinical manifestations of laryngopharyngeal reflux [ J]. Ear Nose Throat J, 2002, 81 (9 Suppl 2) : 19-23.
  • 3Horn C, Vaezi MF. Extra-esophageal manifestations of gastroesophageal reflux disease: diagnosis and treatment [ J ]. Drugs, 2013, 73(12) : 1281-1295. DOI: 10. 1007/s40265-013- 0101-8.
  • 4Belafsky PC, Postma GN, Koufman JA. The validity and reliability of the reflux finding seore (RFS) [ J ]. Laryngoseope, 2001, 111(8): 1313-1317.
  • 5Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index (RSI) [J]. J Voice, 2002, 16(2) : 274 -277.
  • 6Vincent DA Jr, Garrett JD, Radionoff SL, et ah The proximal probe in esophageal pH monitoring: development of a normative database [J]. J "Voice, 2000, 14(2) : 247-254.
  • 7Postma GN, Belafsky PC, Aviv JE, et ah Laryngopharyngeal reflux testing [J]. Ear Nose Throat J, 2002, 81(9 Suppl 2) : 14-18.
  • 8Reichel O, Issing WJ. Impact of different pH thresholds for 24- hour dual probe pH monitoring in patients with suspected laryngopharyngeal reflux [J]. J La,ngol Otol, 2008, 122(5): 485-489.
  • 9Sun G, Muddana S, Slaughter JC, et al. A new pH catheter for laryngopharyngeal reflux : normal values [ J ]. Laryngoscope, 2009, 119 (8) : 1639-1643. DOI: 10. 1002/lary. 20282.
  • 10Wiener GJ, Tsukashima R, Kelly C, et al. Oropharyngeal pH monitoring for the detection of liquid and aerosolized supracsophageal gastric reflux [ J]. J Voice, 2009, 23 (4) : 498- 504. DOI : 10. 1016/j. jvoice. 2007.12. 005.

共引文献171

同被引文献84

引证文献11

二级引证文献92

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部