摘要
目的:对中药组方治疗糖尿病药理研究进展进行综述。方法:查阅近年来有关中药组方治疗糖尿病药理研究文献,并对其分析整理。结果及结论:目前中药组方治疗糖尿病药理作用机制:1)通过保护胰岛β细胞,增加胰岛素受体数目,促进胰岛素受体相关蛋白表达和胰岛素分泌;2)激活糖代谢的相关酶,促使周围组织及靶器官对糖的利用;3)清除自由基及抗脂质过氧化过程作用;4)治疗肾脏、视网膜病变等糖尿病并发症。
Objective：To review the pharmacological researches on TCM（traditional Chinese medicine）herbal formula in treating diabetes.Methods：Collecting and analyzing TCMpharmacological researches of TCMherbal formula in treating diabetes in recent years.Results：The pharmacological mechanism of herbal formula in treating diabetes are as follows：1）Protecting islet βcells and increasing the number of insulin receptors.Then promoting insulin receptor-related protein expression and insulin secretion;2）Ac-tivating glucose enzymes and increasing glucose intake of peripheral tissues and target organs;3）Purging free radical and antioxi-dant;4）treating kidney and retina complications of diabetes.Conclusion：Herbal formula pharmacological researches have a-chieved great progress in recent years.
作者
戴卫波
梅全喜
李乐愚
Dai Weibo Mei Quanxi Li Leyu(TCM Pharmacology Laboratory of Zhongshan Hospital affilated to Guangzhou University of Chinese Medicine ,Zhongshan 528400, China Endocrine System Academy in Zhongshan Hospital affilated to Guangzhou University of Chinese Medicine, Zhongshan 528400, China)
出处
《世界中医药》
CAS
2016年第6期1122-1125,共4页
World Chinese Medicine
基金
广东省中医药局立项资助项目(编号:20141282)
广东省中山市科技基金重点资助项目(编号:2014A1FC004)
关键词
糖尿病
中药组方
药理作用
研究进展
Diabetes
Traditional Chinese medicine prescription
Pharmacological effects
Research progress
