摘要
目的评价盐酸多奈哌齐治疗老年痴呆的临床效果。方法我院收治老年痴呆患者共80例作为调查对象。对照组40例患者接受常规治疗;观察组40例患者除了常规治疗外,联合盐酸多奈哌齐进行治疗,分析比较两组患者的临床治疗效果。结果治疗前,两组患者的MMSE评分及ADL评分比较差异无统计学意义(P>0.05);而治疗12周比较,观察组患者的MMSE评分及ADL评分改善优于对照组,组间差异有统计学意义(P<0.05)。结论盐酸多奈哌齐治疗老年痴呆效果优,安全性高。
Objective To evaluate the clinical effect of donepezil hydrochloride in the treatment of senile dementia.Methods Atotal of 80 cases of senile dementia were treated in our hospital. The control group（40 cases）were treated with conventional therapy,observation group of 40 patients in addition to conventional treatment,combined with donepezil hydrochloride treatment and between the two groups of patients with clinical therapeutic effect were compared.Results Before treatment,two groups of patients with the scores of MMSE and ADL score had no significant difference（P〉0.05）,and 12 weeks of treatment,the observation group of patients with the scores of MMSE and ADL score were better than the control group,the difference exist significant difference（P〈0.05）.Conclusion Donepezil hydrochloride in the treatment of senile dementia with obvious effect,high safety.
出处
《中国卫生标准管理》
2016年第17期100-101,共2页
China Health Standard Management
关键词
盐酸多奈哌齐
老年痴呆
疗效
Donepezil hydrochloride
Senile dementia
Curative effect
