摘要
目的了解佛冈地区的结直肠癌(CRC)患病情况并探讨其影响因素。方法在佛冈县随机抽选48个村或社区作为调查点。先统一发放调查问卷以确定高危人群,然后以粪便隐血试验作为初筛。初筛阳性者以结肠镜检作为复筛以确诊,并采用logistic回归分析影响CRC发生的因素。结果筛查目标为47 400人,回收有效问卷34 286份,顺应率为72.33%;接受初筛26 572人,阳性1 662人,阳性率6.25%;接受结肠镜检980例,发现结直肠癌35例(3.57%);高亚硝酸盐(OR=2.073)、高脂饮食(OR=2.462)和胆囊结石(OR=2.659)为CRC的危险因素,高膳食纤维(OR=0.637)为保护因素。结论结直肠癌筛查能够有效地从无症状人群中找到结直肠癌患者,利于早期治疗,提高预后。佛冈地区居民的CRC筛查依从性较低,应注意加强健康教育。
Objective To investigate the prevalence of colorectal cancer （ CRC ） in Fogang District and to explore its influencing factors. Methods Forty-eight villages or communities in Fogang District were randomly selected as the survey points. The high -risk population was identified by a unified questionnaire survey, and then received the fecal occult blood test as a preliminary screening, and those with positive results were further re-screened by colonoscopy for confirmatory diagnosis. Factors affecting the incidence of CRC were analyzed by logistic regression analysis. Results Totally, 47,400 residents were recruited, and 34,286 effective questionnaires were retrieved, with the compliance rate of 72.33%. 26,572 participants accepted the preliminary screening and 1,662 got positive results, with the positive rate of 6.25%. 980 participants accepted the eolonoscopy and 35 （3.57%） were found to have colorectal cancer. High nitrite diet（ OR = 2.073） , high fat diet （OR = 2.462） and gallbladder stones （OR = 2. 659） were the risk factors for CRC, and high dietary fiber （ OR = 0.637 ） was the protective factor. Conclusions Colorectal cancer screening can effectively identify patients with colorectal cancer among the asymptomatic populations, which is conducive to early treatment and prognosis of the colorectal cancer patients . CRC screening compliance in residents in Fogang District is relatively low, and related health education should be strengthened.
出处
《实用预防医学》
CAS
2016年第10期1211-1213,共3页
Practical Preventive Medicine
基金
清远市科技计划项目(2014B141)
关键词
结直肠癌
筛查
危险因素
Colorectal cancer
Screening
Risk factors
