摘要
目的评价腹腔镜结直肠癌手术后并发症发生情况,并与开腹结直肠癌手术比较。方法采用Meta分析方法对2001-2010年发表的有关腹腔镜与开腹手术治疗结直肠癌术后并发症的研究文献进行综合分析,通过计算合并比值比（OR）以及95%置信区间（95%CI）进行评价。结果统计分析文献13篇,累计病例腹腔镜组2 194例,开放手术2 404例。比较结果为：（1）腹腔镜组心脏并发症发生率比开腹组低（OR=0.49,95%CI：0.25~0.96,P=0.04）。（2）其他两种并发症发生率差异无统计学意义（包括术后吻合口漏：OR=1.02,95%CI：0.73~1.42,P=0.93;肺部感染：OR=0.81,95%CI：0.60~1.09,P=0.18）。结论 RCTs资料的Meta分析认为腹腔镜结直肠癌手术可以降低手术后心脏并发症的发生率,其他并发症的发生率两组差异无统计学意义。
Objective To evaluate the incidence rates of postoperative complications of laparoscopic resection for colorectal caner,and to compare laparoscopic surgery to conventional laparotomy. Methods According to the inclusion and exclusion criteria set,research papers about domestic laparoscopic and open surgeries on the treatment of complications after colorectal cancer from 2001 to 2010 were collected through the literature search methods,and then were comprehensively analyzed by meta analysis.The odds ratio（OR） and 95% confidence interval（95% CI） were calculated. Results Thirteen articles were selected and evaluated.There were 2,194 cases of laparoscopic resection and 2,404 cases of open surgery in total.The incidence rates of postoperative complications of the two groups were as follows： the incidence rate of cardiac complications in laparoscopic group was lower than that of open surgery group（OR=0.49,95%CI： 0.25-0.96,P=0.04）;there was no statistically significant differences in the other complications between the two groups（fistula of anastomotic stoma： OR=1.02,95%CI：0.73-1.42,P=0.93;infection of the respiratory system： OR=0.81,95%CI： 0.60-1.09,P=0.18）. Conclusions The results of meta-analysis show that the laparoscopic resection for colorectal cancer can reduce the incidence rate of cardiac complications and there is no statistically significant difference in the other complications between the two groups.
出处
《实用预防医学》
CAS
2012年第3期417-420,共4页
Practical Preventive Medicine
