摘要
目的探讨高通量血液透析治疗老年慢性。肾衰竭的临床疗效。方法纳入2014年1月～2015年12月在我院行血液透析的老年慢性肾衰竭患者70例，根据透析方式的不同分为研究组与对照组。研究组实施高通量血液透析治疗，对照组实施常规血液透析滤过治疗。观察两组患者治疗前后血红蛋白（Hb）、血肌酐（Scr）、尿素氮（BUN）、白蛋白（Alb）、甘油三脂（TG）、血钙（Ca）、血磷（P）、甲状旁腺素（iPTH）水平等，同时观察患者自觉症状情况。结果治疗前，两组患者Hb、Ser、BNU、Alb、TG、Ca、P、iPTH水平差异均无统计学意义（P〉0．05）。治疗后，研究组Hb、Ser、BNU、Alb、TG、P、iPTH水平分别为（98．2±10．2）g／L、（559．1±294．0）μmol／L、（21．4±5．6）mmol／L、（36．9±3．2）g／L、（1．4±1．0）mmol／L、（1．3±0．3）mmol／L、（402．6±224．4）pg/mL，对照组分别为（90．9±9．4）g／L、（706．0±314．5）μmol／L、（27．6±6．0）mmol／L、（33．0±2．7）g／L、（2．0±1．2）mmol／L、（1．7±0．5）mmol／L、（523．2±278_3）pg／mL，差异均有统计学意义（P〈0．05）；研究组治疗后乏力、骨关节痛、皮肤瘙痒、纳差等自觉症症状发生率分别为11．43％、0、8．57％、17．14％，对照组分别为31．43％、14．29％、28．57％、40．00％，差异均有统计学意义（P〈0．05）。结论老年慢性肾衰竭采用高通量血液透析进行治疗，能够有效提高血液透析的效果，改善自觉症状，值得推广。
Objective To explore the curative effect of high-flux hemodialysis in the treatment of elderly patients with chronic renal failure. Methods 70 cases of elderly patients with chronic renal failure undergoing hemodialysis in our hospital from January 2014 to December 2015 were divided into study group and control group by the differences of dialysis methods. Patients in the study group were treated with high-flux hemodialysis, and patients in the control group were treated with conventional hemodialysis and hemodiafihration. Hemoglobin （HB）, serum creatinine （SCR） and blood urea nitrogen （BUN）, albumin （ALB）, glycerin （TG）, calcium （CA）, phosphorus （P）, parathyroid hormone （iPTH） level before and after the treatment of the two groups were compared. And the subjective symptoms of the two groups were observed. Results Before the treatment, HB, SCR and BUN, ALB, TG, CA, P, iPTH level of the two groups were all not significant （P 〉 0.05）. After the treatment, HB, SCR and BUN, ALB, TG, CA, P, iPTH level of the study group respectively were （98.2 ± 10.2）g/L, （559.1 ± 294.0） μmol/L, （21.4 ± 5.6） mmol/L, （36.9 ± 3.2）g/L, （1.4 ± 1.0） mmol/L, （1.3 ± 0.3） mmol/L （402.6 ± 224.4）pg/mL. And those of the control group respectively were （90.9 ± 9.4）g/L, （706.0 ± 314.5） μmol/L, （27.6 ± 6.0）mmol/L, （33.0 ± 2.7）g/L, （2.0 ± 1.2）mmol/ L, （1.7 ± 0.5）mmol/L, （523.2 ± 278.3）pg/mL. The differences were all significant （P 〈 0.05）. The incidence rates of fatigue, bone and joint pain, pruritus, anorexia and other conscious symptoms after the treatment of the study group respectively were 11.43%, 0, 8.57%, 17.14%. And those of the control group respectively were 31.43%, 14.29%, 28.57%, 40.00%. The differences were all significant（P 〈 0.05）. Conclusion High-flux hemodialysis in the treatment of elderly patients with chronic renal failure could effectively improve the effect of hemodialysis and improve conscious symptoms. It was worthy of promoting.
出处
《中国医药科学》
2016年第15期194-196,共3页
China Medicine And Pharmacy
关键词
高通量
血液透析
老年
慢性肾衰竭
High-flux
Hemodialysis
Elderly patients
Chronic renal failure
