摘要
双胎妊娠为高危妊娠,其子痫前期及子痫的发病率高于单胎妊娠,且近年随着辅助生殖技术的广泛应用双胎妊娠发生率明显增加,双胎妊娠子痫前期及子痫发生率也随之增加。双胎妊娠子痫前期及子痫是全球范围内严重影响母儿健康的疾病,国内外关于双胎妊娠子痫前期及子痫危险因素的研究发现,高龄、初产妇、种族、绒毛膜性、受精卵卵型、体外受精-胚胎移植(IVF-ET)、孕前高体质量指数均为其常见的危险因素。若双胎妊娠存在以上危险因素,其发生子痫前期和子痫的风险增加,应采取有效的针对性措施,降低双胎妊娠子痫前期和子痫的发病率,改善发病患者的不良预后。综述双胎妊娠并发子痫前期及子痫的危险因素,为今后的双胎妊娠围生期保健提供重要参考依据。
Twin pregnancy is high-risk pregnancy. Studies found that the incidence of pre-eclampsia and eclampsia intwin pregnancies is higher than that in singleton pregnancies. With assisted reproductive technology the number and rate of twinbirths continues to increase in recent years. The pre-eclampsia and eclampsia of twin pregnancies have a serious impact onglobal worldwide maternal and fetal pregnancy outcomes. There are many studies on the disease risk factors at home and abroad.The results showed thatElder, prim parity, race, chorionic, fertilized egg type, in vitro fertilization-embryo transfer （IVF-ET）,high pre-pregnancy body mass index （BMI） were the risk factors of twin pregnancies with pre-eclampsia and eclampsia. Theincidence of pre-eclampsia and eclampsia will increase if twin pregnant have these risk factors. Effective measures should betaken to improve the adverse outcomes and reduce the incidences of twin pregnancy pre-eclampsia and eclampsia. This reviewfocused on summarizing the risk factors of pre -eclampsia and eclampsia of twin pregnancies, in order to provide importantreferences for twin pregnancies during perinatal period in the future.
出处
《国际妇产科学杂志》
CAS
2016年第4期385-387,共3页
Journal of International Obstetrics and Gynecology
基金
国家卫生计生委公益性卫生行业科研项目(201402006)
关键词
双生
妊娠
多胎
先兆子痫
子痫
危险因素
Twins
Pregnancy, multiple
Pre-eclampsia
Eclampsia
Risk factors
