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循环纤维细胞与肺部疾病相关性研究进展 被引量:3

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摘要 循环纤维细胞是一类来源于骨髓存在于外周血中的间充质祖细胞,主要表达成纤维细胞、单核细胞以及造血祖细胞的表面标志,可以迁移定居于组织中进一步分化为纤维细胞和肌成纤维细胞,生成和分泌胶原蛋白和其他基质蛋白,参与组织损伤、修复和重建。近年来大量实验研究结果表明,循环纤维细胞的数量、迁移以及分化与以炎症和大量胶原沉积为特征的肺部疾病密切相关。
出处 《国际检验医学杂志》 CAS 2016年第16期2289-2292,共4页 International Journal of Laboratory Medicine
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