2Logroscino G, Traynor B J, Hardiman O, et al. Incidence of amyotrophic lateral sclerosis in Europe [ J ]. J Neurol Neurosurg Psychiatry, 2010,81 ( 4 ) : 385-390.
3Wijesekera LC, Mathers S, Tahnan P, et al. Natural history and clinical features of the flail arm and flail leg ALS variants [ J ]. Neurology, 2009,72(12) :1087-1094.
4Chen L, Zhang B, Chen R, et al. Natural history and clinical features of sporadic amyotrophic lateral sclerosis in China [ J ]. J Neurol Neurosurg Psychiatry, 2015,86 (10) : 1075-1081.
5Turner MR, Hardiman O, Benatar M, et al. Controversies and priorities in amyntrophic lateral sclerosis[ J]. Lancet Neuro1,2013, 12(3) :310-322.
6Robberecht W, Philips T. The changing scene of arnyotrophic lateral sclerosis[J]. Nat Rev Neurosci, 2013,14 (4) :248-264.
7He J, Mangelsdorf M, Fan D, et al. Amyotrophic I,ateral Sclerosis Genetic Studies: From Genome-wide Association Mapping to Genome Sequencing [ J ]. Neuroscientist, 2015,21 (6) :599-615.
8Neumann M, Sampathu DM, Kwong LK, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis [ J ]. Science, 2006,314 ( 5796 ) : 130-133.
9Liscic RM, Breljak D. Molecular basis of amyotvphic lateral sclerosis[ J]. Prog Neuropsychopharmacol Biol Psychiatry, 2011, 35(2) :370-372.
10Renton AE, Chit A, Traynor BJ. State of play in amyotrophic lateral sclerosis genetics [ J ]. Nat Nem'osci, 2014,17 ( 1 ) : 17-23.
3de Carvalho M, Dengler R, Eisen A, et al. Electrodiagnostic criteria for diagnosis of ALS. Clin Neurophysiol,2008, 119:497-503.
4Brooks BR, Miller RG, Swash M, et al. World Federation of Neurology Research Group on Motor Neuron Diseases. El Escorial revisited:revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord, 2000. 1:293-299.
5de Carvalho M, Swash M. Faseiculation potentials: a study of amyotrophic lateral sclerosis and other neurogenic disorders. Muscle Nerve, 1998,21:336-344.
6de Carvalho M. Pathophysiological signicance of fasciculations in the early diagnosis of ALS. Amyotroph Lateral Scler Other Motor Neuron Disord ,2000,1Suppl 1 : S43-S46.
7TraynorB J, Codd MB, Corr B, et al. Clinical features of amyotrophic lateral sclerosis according to the EI Escorial criteria and Airlie House diagnostic criteria, Arch Neuro1,2000,57:1171-1176.
8Guiloff R J, Modarres-Sadeghi H. Voluntary activation and fibre density of fasciculations in motor neuron disease. Ann Neurol, 1992, 31:416-424.
9Eisen A, Krieger C. Amyotrophic lateral sclerosis:a synthesis of research and clinical practice. Cambridge: Cambridge University Press, 1998 : 151-157.
10de Carvalho M, Swash M. Fasciculation potentials: a study of amyotrophic lateral sclerosis and other neurogenic disorders. Muscle Nerve, 1997,21:336-344.