摘要
目的:观察补阳还五汤应用不同剂量黄芪治疗老年脑卒中患者的疗效。方法:选取70例脑卒中老年患者作为研究对象,按随机数字表法分为低剂量组与高剂量组。2组均应用补阳还五汤进行治疗,低剂量组黄芪为45 g,高剂量组黄芪为120 g,比较2组治疗前后的中医证候积分、神经功能缺损评分、实验室指标(内皮素、血沉、全血黏度、血浆黏度)与临床疗效。结果:高剂量组总有效率为88.6%,高于低剂量组的68.6%,差异有统计学意义(P<0.05)。治疗后,2组中医证候积分、神经功能缺损评分评分均较治疗前降低(P<0.05),高剂量组2项评分均低于低剂量组(P<0.05)。2组内皮素、血沉、全血黏度、血浆黏度均较治疗前降低(P<0.05),高剂量组各项实验室指标值均低于低剂量组(P<0.05)。结论:补阳还五汤中应用高剂量(120 g)黄芪可更有效缓解患者的临床症状与改善神经功能缺损,利于血液黏度的降低,效果更佳。
Objective：To observe the curative effect of Buyang Huanwu tang with different dose of astragalus for elderly cerebral apoplectic. Methods： Seventy cases of elderly patients with cerebral apoplectic as research objects, were divided randomly into low- dose group and high- dose group in accordance with the random number table. The patients in both groups were all treated with Buyang Huanwu tang,which the astragalus weight in low- dose group was 45 g and that in high- dose group was 120 g. Chinese Medicine（CM） syndrome scores,neurological impairment evaluation,laboratory index（endothelin,erythrocyte sedimentation rate,whole blood viscosity,and plasma viscosity） and clinical effect were compared. Results：The total effective rate in high- dose group was 88.6%,higher than that of 68.6% in low- dose group（P〈0.05）. After treatment,the CM syndrome scores and neurological impairment scores in both groups were decreased（P〈0.05）,and the those scores in high- dose group were all lower than those in low- dose group（P〈0.05）. The endothelin,erythrocyte sedimentation rate,whole blood viscosity and plasma viscosity in both groups were decreased（P〈0.05）. Every laboratory index in high- dose group were all lower than those in low- dose group（P〈0.05）. Conclusion：Buyang Huanwu tang with high dose of astragalus（120 g） can relieve clinical symptoms of patients and improve neurologic impairment more effectively. This is beneficial to reduce blood viscosity with nice effect.
出处
《新中医》
CAS
2016年第5期48-50,共3页
New Chinese Medicine
关键词
脑卒中
老年
补阳还五汤
黄芪
剂量
Cerebral apoplectic
Elderly
Buyang Huanwu tang
Astragalus
Dose
