摘要
目的评价无创正压通气治疗重症支气管哮喘急性发作患者的疗效。方法 60例支气管哮喘急性发作患者随机分为2组。对照组给予常规治疗,观察组在此基础上使用无创机械通气。比较两组治疗前后血气指标、临床结局及不良反应。结果两组治疗后12、24、48 h动脉pH值、PaO_2、PaCO_2均较治疗前改善,观察组更显著(P<0.05或0.01)。两组治愈率、气管插管率、病死率及不良反应差异均无统计学意义(P>0.05)。结论无创正压通气对重症支气管哮喘急性发作有一定疗效。
Objective To evaluate the clinical efficacy of noninvasive positive pressure ventilation（NPPV） in acute attack of severe bronchial asthma（SBA）. Methods Sixty patients with acute attack of SBA were randomly divided into 2 groups. Control group received conventional treatment,whereas observation group accepted with additional NPPV. Blood gas indexes,clinical outcomes and adverse reactions were compared between 2 groups. Results The pH,PaO2 and PaCO2 of arterial blood were improved at 12 h,24 h and 48 h after treatment in 2 groups,especially in observation group（P〈0.01-0.05）. The cure rate,endotracheal intubation,mortality,and adverse reactions showed no difference in both groups（P〈0.05）. Conclusion NPPV may be beneficial for acute attack of SBA.
出处
《广东医学院学报》
2015年第6期676-678,共3页
Journal of Guangdong Medical College
关键词
无创正压通气
支气管哮喘
noninvasive positive pressure ventilation
bronchial asthma
