摘要
目的探讨轻度哮喘急性发作病人应用无创正压通气(NPPV)的临床疗效。方法36例支气管哮喘急性发作患者,男21例,女15例,平均年龄(44±15)岁,随机分组,治疗组、对照组,各18例。在抗感染、平喘、激素等常规治疗的基础上,给予NPPV。多参数监护仪持续监测呼吸频率(RR)、心率(HR)、血氧饱和度(SaO2),并在通气前、通气后30min、1、2h分别取其具体数值进行统计,各组数据运用SPSS11.0统计软件进行处理。结果治疗后30min:RR、HR、SaO2的两组间差异均表现出显著性意义(t值分别为:t=2.738,t=2.191,t=2.410,P<0.05)。治疗后1、2h:两组的RR、HR、SaO2在监测数据上虽然有明显的差异,但无统计学意义(P>0.05)。结论NPPV运用到哮喘急性发作的轻度患者是有益的。哮喘急性发作患者无论病情轻重,都有不同程度的呼吸肌疲劳,NPPV能缓解呼吸肌疲劳、提高氧合水平,临床症状明显缓解,患者耐受性好、乐于接受,可做进一步探讨。
Objective To evaluate the effect of noninvasive positive pressure ventilation (NPPV) in asthma during an acute attack.Methods A randomized, placebo-controlled and prospective study was conducted.Thirty-six cases were divided into 2 groups (an experimental group and a placebo-controlled group) with 18 cases in each group.Being maintained on routine treatment,the experimental group was also treated with NPPV. While the placebo-controlled group was assigned to receive only on routine treatment.Results There were significant differences between experimental group and placebo-controlled group in heart rate and respiratory rate.Conclusion It was beneficial for the patient with asthma during acute attack to be treated with NPPV, though those patients suffering from light asthma.
出处
《重庆医学》
CAS
CSCD
2005年第7期1057-1058,共2页
Chongqing medicine
关键词
支气管哮喘
无创正压通气
治疗
asthma
noninvasive positive pressure ventilation
treatment
