摘要
目的探讨脓毒症患者血清降钙素原检测的临床意义。方法回顾性分析2013年7月～2015年6月细菌感染脓毒症患者89例的临床资料,根据危重程度分为早期组、重症组和休克组。比较各组白细胞计数、C反应蛋白、血清降钙素原水平以及APACHEⅡ评分,分析血清降钙素原与APACHEⅡ之间的相关性。结果 Pearson相关分析结果显示,患者PCT水平与APACHEⅡ评分具有显著正相关（r=0.663,P〈0.01）。休克组及重症组患者PCT、CRP、WBC及APACHEⅡ评分显著高于早期组,休克组显著高于重症组,差异均有统计学意义（P〈0.01）。PCT水平越高,则死亡率越高（P〈0.05）;PCT水平越高,抗感染治疗时间以及住院时间越长（P〈0.05）。结论 PCT水平检测能够判断脓毒症患者的病情,可用于预后的判断。
Objective To discuss clinical significance of PCT detection in patients with sepsis. Methods Clinical data of 89 cases with sepsis from July 2013 to June 2015 were respectively analyzed, and all cases were divided into early group, severe group and shock group according to patient＇s condition. WBC, CRP, PCT and APACHEⅡ score of three groups were compared, and relationship of PCT and APACHE Ⅱ was analyzed. Results Pearson correlation analysis showed that PCT was positive correlation with APACHEⅡ score（r=0.663,P〈0.01）. WBC, CRP, PCT and APACHEⅡscore of shock group and severe group were higher than early group, and those of shock group were higher than severe group too, which showed significant difference（P〈0.01）. The higher of PCT level, the higher was the mortality rate（P〈0.05）; The higher of PCT level, the longer anti-infection treatment time and hospital stay（P〈0.05）. Conclusion PCT levels in sepsis can determine the patient＇s condition, evaluate prognosis.
出处
《中国现代医生》
2016年第7期59-61,共3页
China Modern Doctor
基金
河南大学第一附属医院科研项目(2012年第14号)
