摘要
A neolignan codonopiloneolignanin A（1） with a novel 2,9：20,9：7,70-tricyclo-8,90-neolignane skeleton was isolated from an aqueous extract of the Codonopsis pilosula roots. Its structure including the absolute configuration was elucidated by extensive spectroscopic analysis, including 2D NMR and electronic circular dichroism calculation. The proposed biosynthetic pathway of compound 1 is also discussed.
A neolignan codonopiloneolignanin A（1） with a novel 2,9：20,9：7,70-tricyclo-8,90-neolignane skeleton was isolated from an aqueous extract of the Codonopsis pilosula roots. Its structure including the absolute configuration was elucidated by extensive spectroscopic analysis, including 2D NMR and electronic circular dichroism calculation. The proposed biosynthetic pathway of compound 1 is also discussed.
基金
Financial support from the National Natural Science Foundation of China (Nos. 30825044, 21132009)
the Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT, No. IRT1007)
the National Science and Technology Project of China (Nos. 2012ZX09301002-002, 2011ZX0 9307-002-01) are acknowledged
