血清PCT联合痰培养检测在呼吸道感染疾病中的应用被引量：6

Application of Serum PCT Combined with Sputum Culture to Detection of Respiratory Tract Infection

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摘要目的:研究血清降钙素原(PCT)联合痰培养检测在呼吸道感染疾病中的应用价值。方法:选择2012年1月至2014年12月在我院接受治疗的呼吸道感染患者100例进行研究。分析痰培养菌群的分布情况以及PCT的检测结果,对比痰培养细菌感染者及真菌感染者的菌种分类及PCT检测结果。结果:检出病原菌的患者PCT水平均分别显著高于正常菌群及未见细菌生长的患者,差异均有统计学意义(均P<0.05)。细菌感染PCT阳性比例与真菌感染相比,差异无统计学意义(P>0.05)。细菌感染中,革兰氏阳性菌的PCT水平(0.74±0.33μg/L)与革兰氏阴性菌(0.72±0.24μg/L)对比,差异无统计学意义(P>0.05)。真菌感染中,白假丝酵母菌及烟曲霉菌的PCT阳性比例最高,分别为60.00%及80.00%。结论:血清PCT与痰培养检测应用于评价有呼吸道感染的患者病情,具有一定的反馈意义,但无法确定患者的呼吸道感染究竟是细菌感染亦或是真菌感染。 Objective： To study the application value of serum procalcitonin（PCT） combined with sputum culture in the detection of respiratory tract infection. Methods： A total of 100 patients with respiratory tract infection, who were treated in Panjin Center Hospital from January 2012 to December 2014, were chosen as research subjects. The flora distribution of sputum culture and the corresponding PCT levels were analyzed. The bacterial species distribution of bacterial infection and fungal infection of sputum culture and the corresponding PCT levels were compared. Results： The PCT levels of patients with detected pathogenic bacteria were significantly higher than those of patients with normal flora and no bacterial growth, the differences were statistically significant（P〈0.05）. PCT positive rate of patients with bacterial infection had no significant difference compared with the patients with fungal infection（P〉0.05）. In bacterial infection, there was no statistically significant difference between the ratio of PCT level of the positive gram bacteria（0.74 ±0.33 μg/L）to PCT level of the negative gram bacteria（0.72±0.24 μg/L）（P〉0.05）. The PCT positive rates of candida albicans（60%） and aspergillus starter（80%） were the highest in fungal infection. Conclusion： Applicatin of detection of serum PCT plus sputum culture to the evaluation of patients with respiratory tract infection has a certain feedback value, but it can not judge whether it is bacterial infection or fungal infection.

作者石雪颖谢宇光薛海英吕国良孙振玲

机构地区盘锦市中心医院呼吸内科盘山县人民医院内科盘锦市中心医院感染性疾病科

出处《现代生物医学进展》 CAS 2016年第2期323-325,385,共4页 Progress in Modern Biomedicine

关键词血清PCT 痰培养呼吸道感染疾病应用 Serum PCT Sputum culture Respiratory tract infection Application

分类号 R56 [医药卫生—呼吸系统]

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