摘要
目的探讨老年冠心病患者血清同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)水平与冠脉病变程度的相关性。方法 214例经冠状动脉造影确诊的老年冠心病患者,按照不同病变血管数分为单支病变组、双支病变组、三支病变组。选择42例同期健康体检者为对照组,检测入院时血清Hcy及hs-CRP浓度。结果冠心病组Hcy及hs-CRP浓度高于对照组,三支病变组Hcy及hs-CRP水平显著高于双支、单支病变组(P<0.05),双支病变组高于单支病变组(P<0.05);随着冠脉病变Gensini积分的增加,血清Hcy及hs-CRP水平明显升高(P<0.05)。结论 Hcy、hs-CRP对老年冠心病的诊断及病变程度有一定的预测价值。
Objective To investigate the relationship of homocysteine（ Hcy） and high-sensitivity C-reactive protein（ hs-CRP） levels and the severity of coronary artery disease in the elderly patients with coronary heart disease（ CHD）.Methods 214 elderly patients with CHD diagnosed by coronary angiography were divided into single vessel disease group,two vessels disease group,three vessels disease group,according to the number of vascular lesions. Forty-two healthy subjects at the same period were selected as control group. The serum levels of Hcy and hs-CRP were detected at admission.Results The levels of Hcy and hs-CRP in the patients with CHD were higher than those in the control group,The levels of Hcy and hs-CRP were highest in three vessels disease group,followed by two vessels disease group and single vessel disease group（ P〈0. 05）. With the increase of Gensini score of coronary artery disease,the levels of serum Hcy and hs-CRP increased significantly（ P〈0. 05）. Conclusions The levels of Hcy and hs-CRP can be used to predict the severity of coronary artery disease in the elderly patients with coronary heart disease.
出处
《实用老年医学》
CAS
2016年第2期139-141,共3页
Practical Geriatrics
基金
承德市科学技术研究与发展计划项目(20122159)
关键词
冠心病
同型半胱氨酸
超敏C反应蛋白
coronary heart disease
homocysteine
high-sensitivity C-reactive protein
