摘要
作者研究了重症肌无力患者血清对正常人红细胞免疫粘附功能的抑制作用,发现:65％的患者血清对正常人红细胞C_3b(RBC-C_3b)受体花环的形成具有抑制作用。全身型患者的血清抑制活性明显高于眼型患者(P<0.01),提示血清抑制作用与疾病的临床类型有关。作者还发现血清抑制活性与患者的RBC-C_3b受体花环率降低以及循环免疫复合物(CIC)水平升高有一定关系。并证明患者血清中的CIC本身就具有红细胞免疫粘附抑制活性。
The serum inhibitory activities onRBC-C_3b receptor rosett of healthy indi-viduals were studied in myasthenia gravis(MG) patients. The serum inhibitory ac-tivities appeared in 65% of MG patients.The serum inhibitory activities of general-ized type MG were higher than those ofocuiar type MG.It was also found that theserum inhibitory activities were correlatedwith the RBC-C_3b receptor rosett rate andimmmune complex (CIC). Furthermore, itwas identified that the CIC of MG serumspossessed the inhibitory activity on RBC-C_3b receptor rosett.
出处
《华西医科大学学报》
CAS
CSCD
1989年第4期381-383,共3页
Journal of West China University of Medical Sciences
基金
国家自然科学基金
