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类固醇激素治疗在难治性癫痫中的应用 被引量:6

Use of corticosteroids in refractory epilepsy
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摘要 难治性癫痫患儿对抗癫痫药物无效,给其身心发育造成巨大影响。寻找难治性癫痫患儿的替代治疗方案很有必要,类固醇激素作为治疗癫痫的药物之一,对其中一部分难治性癫痫有良好疗效。临床医生应了解并掌握类固醇激素治疗难治性癫痫的适应证、剂量、疗程等内容。 Epilepsy is a common neurological disease in children. Although most patients are seizure-free after treatment of antiepileptie drugs, a few patients have no response, called refractory epilepsy. Refractory epilepsy has huge influence on patients' physical and mental development. It is necessary to find an alternative for them. As one of the drugs for epilepsy, corticosteroids have good effect on refractory epilepsy. The clinician should know the indications, dose and course of cortico- steroids used in refractory epilepsy.
作者 潘岗 周水珍
出处 《中国实用儿科杂志》 CSCD 北大核心 2016年第1期36-41,共6页 Chinese Journal of Practical Pediatrics
关键词 难治性癫痫 类固醇激素 适应证 剂量 疗程 refractory epilepsy corticosteroids indications dose course
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  • 1张炜华,邹丽萍,曾敏,王红梅,姬曼.母体免疫球蛋白G对N-甲基-D-天冬氨酸诱导婴儿痉挛大鼠模型的作用及其对脑内促肾上腺皮质激素表达的影响[J].实用儿科临床杂志,2006,21(7):426-427. 被引量:3
  • 2Pellock J M, Hrachovy R, Shinnar S, et al. Infantile spasms : a U. S. consensus report [ J ]. Epilepsia, 2010, 51 ( 10 ) : 2175 - 2189.
  • 3Kwan P, Brodie M J. Early identification of refractory epilepsy[ J]. N Engl J Med, 2000, 342(5) : 314 -319.
  • 4Watemberg N. Infantile spasms : treatment challenges [ J ]. Curt Treat Options Neurol, 2012, 14(4) : 322 -331.
  • 5I Tsao C Y. Current trends in the treatment of infantile spasms[ J]. Neu- ropsychiatr Dis Treat, 2009, 5 : 289 - 299.
  • 6Vigevano F, Cilio M R. Vigabatrin versusACTH as first-line treatment for infantile spasms : a randomized, prospective study [J ]. Epilepsia, 1997, 38(12) : 1270-1274.
  • 7Hancock E, Osborne J P. Vigabatrin in the treatment of infantile spasms in tuberous sclerosis: literature review [ J]. J Child Neurol, 1999, 14(2) : 71 -74.
  • 8Appleton R E, Peters A C, Mumford J P, et al. Randomised, placebo- controlled study of vigabatrin as first-line treatment of infantile spasms [J]. Epilepsia, 1999, 40(11) : 1627 -1633.
  • 9Ibrahim S, Gulab S, Ishaque S, et al. Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country per- spective[J]. BMC Pediatr, 2010, 10: 1.
  • 10Asano E, Chugani D C, Juhasz C, et al. Surgical treatment of West syndrome[ J]. Brain Dev, 2001, 23(7) : 668 -676.

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