摘要
目的研究围产期孕产妇生殖道感染时菌群分布,并了解B族链球菌(GBS)在下生殖道定植特点及耐药情况,为临床预防、治疗围产期母婴相关的细菌感染性疾病提供实验室依据。方法对6 150例围产期孕产妇宫颈分泌物进行培养鉴定,并对分离的GBS进行药敏分析。结果 6 150例孕产妇中,病原菌共检出269例,检出率为4.37%,常见菌以GBS居多,其次为大肠埃希菌、金黄色葡萄球菌和粪肠球菌;GBS对氨苄西林、青霉素、万古霉素高度敏感,敏感率均为100.00%,对克林霉素、四环素的耐药性较高,分别为99.15%、88.98%。结论引起围产期孕产妇生殖道感染的细菌以GBS最多,进行GBS的耐药性分析,对控制细菌耐药性的产生和临床治疗具有重要的意义。
Objective To study the bacteria distribution in genital tract of perinatal women, understand the colonization characteristics and drug resistance of group B streptococcus （GBS） in the lower genital tract, in order to provide lab basis for prevention and treatment of maternal and child related bacterial diseases. Methods The cervical secretions from 6 150 perinatal women were cultured and identified, and drug sensitivity of the isolated GBS was analyzed. Results Among 6 150 perinatal women, 269 cases of pathogenic bacteria were detec- ted and the detection rate was 4. 37% , in which GBS took the majority, followed by Escherichia coli, Staphylococcus aureus and Enterococcus faecalis; GBS was highly sensitive to ampicillin, synercid, penicillin, vancomycin, the sensitivity rates were all 100. 00% , GBS had rela- tively drug resistance to elindamycin, tetracycline, the sensitivity rates were 99. 15%, 88.98%, respectively. Conclusion ＂The bacteria causing infection of reproductive tract in perinatal women was mostly GBS. Analyzing drug resistance of GBS has important significance for controlling bacterial drug resistance and clinical treatment.
出处
《中国妇幼保健》
CAS
2016年第3期565-567,共3页
Maternal and Child Health Care of China
关键词
围产期
生殖道感染
B族链球菌
Perinatal period
Reproductive tract infection
Group B streptococcus
