摘要
目的对老年喉癌患者手术治疗效果及其影响因素进行分析探讨。方法对2009年6月至2014年6月收治的120例老年喉癌患者的临床资料进行回顾性分析。结果经过5年时间的随访,所有患者在1、3年的生存率分别为97.1%(116/120)、71.2%(85/120)。通过单因素分析,结果发现:年龄、肿瘤原发部位、肿瘤大小、淋巴结转移、是否行颈部淋巴结清扫、病理分级、TNM分期、手术方式及治疗方式对患者预后影响具有统计学意义(P<0.05);通过多因素分析,结果发现:肿瘤原发部位、淋巴结转移、TNM分期及治疗方式是影响老年喉癌预后的独立因素。结论肿瘤原发部位、淋巴结转移、TNM分期及治疗方式是影响老年喉癌预后的独立因素。喉功能保全性手术是治疗老年喉癌患者较为理想的手术方法,其中早期诊断与早期治疗对提高患者生存率具有非常重要的意义。
Objective To explore the effect of surgical treatment for elderly patients with laryngeal cancer and its affecting factors. Methods There were 120 elderly patients with laryngeal cancer during June 2009 to June 2014 admitted to this hospital for treatment,and their clinical data were retrospectively analyzed. Results After 5 years of follow up,the 1 yr and 3 yr survival rates in these patients were 97. 1% and 71. 2%respectively. Univariate variable analysis showed there were several factors such as age,primary site of tumor,tumor size,metastasis in lymph nodes,pathologic stage,the cleaning of neck lymph nodes,TNM staging,operation procedures and treatment methods affected the prognosis of patients,and the difference in these affecting factors between these 2 groups was statistically significant（ P〈0. 05）. Multivariate analysis showed that there were also several affecting factors which will affect the prognosis of these patients such as primary site of tumor,metastasis in lymph nodes,TNM staging and treatment methods,etc. Conclusion The affecting factors such as primary site of tumor,metastasis in lymph nodes,TNM staging and treatment methods are independent factors which will affect the prognosis of patients. Surgical treatment for preservation of laryngeal function is the ideal operation procedure in treatment of old patients with laryngeal cancer,and the early diagnosis and early treatment have very important significance in improving the survival rate of these patients.
出处
《临床和实验医学杂志》
2016年第1期54-56,共3页
Journal of Clinical and Experimental Medicine
关键词
老年
喉癌
手术治疗
影响因素
Elderly
Laryngeal cancer
Surgical treatment
Affecting factors
