摘要
目的分析脾氨肽对支气管哮喘患者T细胞亚群及Ig E水平的影响。方法选取本院支气管哮喘患者92例为研究对象,依照治疗方法不同分为研究组和对照组各46例,研究组患者给予脾氨肽治疗,对照组患者采取常规治疗。分析患者治疗效果以及T细胞亚群和Ig E水平变化。结果研究组患者治疗总有效率显著高于对照组(P<0.05);治疗前,2组患者T细胞亚群差异无统计学意义(P>0.05);治疗后,研究组患者CD8+显著低于对照组,CD3+、CD4+、CD4/CD8显著高于对照组(P<0.05);研究组患者Ig E水平显著低于对照组(P<0.05)。结论在支气管哮喘患者治疗中采用脾氨肽治疗能够显著改善患者T细胞亚群和Ig E水平,提高患者整体免疫状态。
Objective To analyze and discuss the application effect of spleen aminopeptidase on T cell subsets and Ig E in bronchial asthma patients. Methods A total of 92 patients with bronchial asthma in hospital were selected,and they were divided into control group（ 46 cases） and study group（ 46 cases） according to the treatment. Patients of control group were given conventional treatment,patients of study group were given spleen aminopeptidase,the curative effect,the changes of T cell subsets and Ig E of the two groups were compared. Results The overall response rate in the study group was significantly higher（ P 0. 05）; There were no significant difference in T cell subsets before the treatment in the two groups（ P 0. 05）; CD8＋in the study group was significantly lower than that in the control group,and CD3＋、CD4＋、CD4/ CD8 were significantly higher than that in the control group（ P 0. 05）; Ig E levels in the study group was significantly lower than that in the control group（ P 0. 05）. Conclusion Spleen aminopeptidase for the treatment of patients with bronchial asthma can improve T lymphocyte subsets and Ig E levels,and improve the comprehensive immune state of patients.
出处
《实用临床医药杂志》
CAS
2015年第24期63-65,共3页
Journal of Clinical Medicine in Practice
关键词
脾氨肽
支气管哮喘
T细胞亚群
IGE
spleen aminopeptidase
bronchial asthma
T cell subsets
IgE
