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延髓胶质瘤的显微外科治疗 被引量:2

Microsurgical treatment of medulla oblongata glioma
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摘要 目的探讨延髓胶质瘤的病理特点、显微手术技巧和围手术期处理。方法回顾性分析67例延髓胶质瘤的临床资料,枕下后正中入路48例,远外侧入路16例,枕下乙状窦后入路3例。结果肿瘤全切除10例,次全切除45例,部分切除12例。WHO分级Ⅰ级6例,Ⅱ级41例,Ⅲ级15例,Ⅳ级5例。术后并发症7.4%,术后2周内无死亡病例。随访时间10~84个月,平均33个月。根据寿命表法计算,术后1年、3年、5年生存率分别为77%、49%和39%。结论延髓胶质瘤多为低级别肿瘤,通过积极显微外科治疗可获得良好预后。 Objective To study the pathological features, microsurgical skills and perioperative management of medulla oblongata glioma(MOG). Methods The clinical data of 67 MOG patients were analyzed retrospectively. The posterior median suboccipital approach was chosen in 48 cases, far lateral approach in 16 and suboccipital retrosigmoid approach in 3. Results Complete tumor resection was achieved in 10 cases, subtotal resection in 45 and partial resection in 12. WHO classification gradeⅠwas noted in 6 cases,grade Ⅱ in 41, grade Ⅲ in 15 and grade Ⅳ in 5. The rate of postoperative complications was 7.4%. No patient died in 2 weeks after operation. All the patients were followed-up from 10 to 84 months, with an average of 33 months. According to the life table method, the survival rate of 1-year, 3-years and 5-years was 77%, 49% and 39% respectively. Conclusions MOGs are mostly low-grade tumors. The active microsurgical treatment could get a good outcome.
出处 《中国微侵袭神经外科杂志》 CAS 2015年第12期555-557,共3页 Chinese Journal of Minimally Invasive Neurosurgery
关键词 神经胶质瘤 延髓 显微外科手术 glioma medulla oblongata microsurgery
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参考文献8

  • 1Guillamo JS, Monjour A, Taillandier L, et al. Brainstem gliomas in adults: prognostic factors and classification [J]. Brain, 2001, 124(Pt 12): 2528-2539.
  • 2Reithmeier T, Kuzeawu A, Hentschel B, et ol. Retrospective analysis of 104 histologically proven adult brainstem gliomas: clinical symptoms, therapeutic approaches and prognostic factors [J]. BMC Cancer, 2014, 14:115.
  • 3Rachinger W, Grau S, Holtmannspotter M, et al. Serial stereotactic biopsy of brainstem lesions in adults improves diagnostic accuracy compared with MRI only [J]. J Neurol Neurosurg Psychiatry, 2009, 80(10): 1134-1139.
  • 4Kickingereder P, Willeit P, Simon T, et al. Diagnostic value and safety of stereotactic biopsy for brainstem tumors: a systematic review and meta-analysis of 1480 cases [J]. Neurosurgery, 2013, 72(6): 873-882.
  • 5Muragaki Y, Chernov M, Maruyama T, et al. Low-grade glioma on stereotactic biopsy: how often is the diagnosis accurate [J]? Minim Invasive Neurosurg, 2008, 51(5): 275-279.
  • 6张力伟,王忠诚.脑干胶质瘤治疗现状[J].中国微侵袭神经外科杂志,2010,15(4):145-147. 被引量:19
  • 7张俊廷.脑干肿瘤的手术治疗:回眸与展望[J].中国微侵袭神经外科杂志,2012,17(2):49-51. 被引量:16
  • 8WuJS, Zhou LF, Tang WJ, et al. Clinical evaluation and follow-up outcome of diffusion tensor imaging-based functional neuronavigation: a prospective, controUed study in patients with gliomas involving pyramidal tracts [J]. Neurosurgery, 2007, 61(5): 935-949.

二级参考文献15

  • 1王忠诚,张俊廷,刘阿力.311例脑干胶质瘤的临床特征与手术治疗[J].中国医学科学院学报,2005,27(1):7-12. 被引量:34
  • 2王亮,张俊廷,吴震,贾桂军.脑干海绵状血管瘤的外科治疗进展[J].中国微侵袭神经外科杂志,2007,12(3):139-141. 被引量:19
  • 3Choux M, Lena G, Do L. Brainstem tumors [J]. Pediatric Neurosurgery, 2000, 33:471-479.
  • 4Guillamo JS, Monjour A, Taillandier L, et al. Brainstem gliomas in adults: prognostic factors and classification [J]. Brain, 2001, 124(Pt 12): 2528-2539.
  • 5Albright AL, Packer R J, Zimmerman R, et al. Magnetic resonance scans should replace biopsies for the diagnosis of diffuse brain stem gliomas: a report from the Children's Cancer Group [J]. Neurosurgery, 1993, 33(6): 1026-1030.
  • 6Marcus K J, Dutton SC, Barnes P, et al. A phase I trial of etanidazole and hyperfractionated radiotherapy in children with diffuse brainstem glioma [J]. Int J Radiat Oncol Biol Phys, 2003, 55(5): 1182-1185.
  • 7Jallo GI, Biser-Rohrbaugh A, Freed D. Brainstem gliomas [J]. Childs Nerv Syst, 2004, 20(3): 143-153.
  • 8Kalifa C, Grill J. The therapy of infantile malignant brain tumors: current status [J]? J Neurooncol, 2005, 75(3): 279- 285.
  • 9Broniscer A, Iacono L, Chintagumpala M, et al. Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children [J]. Cancer, 2005, 103 (1): 133-139.
  • 10Hargrave D, Bartels U, Bouffet E. Diffuse brainstem glioma in children: critical review of clinical trials [J]. Lancet Oncol, 2006, 7(3): 241-248.

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