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趋化因子CXCLl2及其受体CXCR4在神经胶质瘤治疗中的作用 被引量：1

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摘要 胶质瘤是中枢神经系统最常见的肿瘤，约占颅内肿瘤的35％-61％，根据瘤细胞的分化情况可分为星形胶质瘤、少突胶质瘤、室管膜瘤、髓母细胞瘤、多形胶质母细胞瘤等。胶质瘤细胞呈浸润性生长，与正常脑组织无明确边界，具有高增殖性和高侵袭性，其病死率高，预后差，患者生存时间短，尤其是胶质母细胞瘤患者的中位生存期仅约为14个月^[1]。
作者 景芳邈 曲迅 刘小梅（编辑）
机构地区 山东大学齐鲁医院临床基础研究所
出处 《中华医学杂志》 CAS CSCD 北大核心 2012年第11期788-790,共3页 National Medical Journal of China
关键词 神经胶质瘤 受体CXCR4 CXCLl2 趋化因子 胶质母细胞瘤 髓母细胞瘤 治疗 中枢神经系统
分类号 R739.41 [医药卫生—肿瘤]
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参考文献25

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二级参考文献20

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共引文献28

同被引文献13

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中华医学杂志
2012年 第11期

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