摘要
毛蕊异黄酮是从蒙古黄芪中分离得到的重要异黄酮类活性化合物,为典型的植物雌激素,能够与机体的雌激素受体结合,产生雌激素样作用,具有明显的抗氧化、抗骨质疏松、抗肿瘤和免疫调节等作用。毛蕊异黄酮由于不良反应小、毒性低、药理作用多样的特点,使其相关的研究成为热点,该文通过文献综述考证毛蕊异黄酮的生物学活性及其作用机制,为该类单体药物临床研究提供了理论依据,有利于单体药物更好的开发应用。
Calycosin,which is a kind of typical phytoestrogen,can bind with estrogen receptor and produce estrogen-like effects.Calycosin were reported to have antioxidant,anti-osteoporosis,anti-tumor and immunomodulating activities. This review covers biological activities and its mechanism of calycosin. It will provide a useful reference for clinical research and rational utilization of monomeric compound.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2015年第22期4339-4345,共7页
China Journal of Chinese Materia Medica
基金
公益性行业(农业)科研专项(201403063)
