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合成新药SC1001钠盐对家兔呼吸频率、心率、直肠温度和皮层电图的影响

EFFECTS OF SYNTHETIC NEW DRUG SC1001-SODIUM ON RESPIRATORY FREQUENCY,HEART RATE,RECTAL TEMPERATURE AND ELECTROCORTICOGRAM IN RABBITS
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摘要 作者用SC1001钠盐(200mg/kg)注入家兔腹腔内,观察其对呼吸频率、心率、直肠温度和皮层电图的影响。实验结果表明,对家兔的呼吸频率、直肠温度有轻微的抑制作用,对中枢神经活动有明显的抑制作用,对心率有加快作用。 Seventeen normal male rabbits weighing1.7-2.8kg were randomly divided into 2groups. The experimental group (ten rabbits)was injected with SC_(1001)Na (200mg/kg,i.p.). The control group(seven rabbits)wasinjected with normal saline of the samevolume. Continuous observations for 6hours were made after injection, withreference to respiratory frequency (RF),heart rate (HR), rectal temperature (RT)and ECoG of these rabbits. The results of experiments indicate thatSC_(1001)Na has a slight inhibitory effect onRF and RT, an obvious inhibitory effect onthe activity of central nervous system, andan accerlerating effect on HR in rabbits.
出处 《华西医科大学学报》 CAS CSCD 1989年第1期28-28,共1页 Journal of West China University of Medical Sciences
关键词 SC1001钠盐 呼吸频率 心率 SC_(1001)-Sodium Respirator frequency Heart rate Rectal temperature Electrocorticogram
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参考文献3

  • 1施新猷,医学动物实验方法,1986年,407页
  • 2团体著者,家畜生理学,1980年,80页
  • 3团体著者,家畜生理学,1978年,138页

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