摘要
目的总结胰十二指肠切除术后胰瘘的预防方法。方法通过检索近年来国内外关于胰十二指肠切除术后胰瘘预防方法的相关文献并做一综述。结果胰瘘是胰十二指肠切除术后常见并发症之一,其主要由于术前持续高黄疸,术中吻合方式的选择,术后早期大量胰液的分泌,胰蛋白酶原被碱性肠液激活,从而消化附近的组织造成胰瘘,胰液流入腹腔而消化腹腔组织,造成严重并发症,甚至死亡。通过药物、术前减黄、术中吻合方式的选择等方面的预防,术后胰瘘的发生率有所下降。结论胰十二指肠切除术后胰瘘的预防是一个综合过程,需贯穿整个围手术期。
Objective To summarize the prevention method for pancreatic fistula following pancreaticoduodenec- tomy. Method Literatures related to the prevention methods for postoperative pancreatic fistula at home and abroad in recent years were retrieved and summarized. Results The pancreatic fistula was a common complication following pancreaticoduodenectomy. It was mainly caused by preoperative continuous high jaundice, selection of intraoperative anastomosis, and early postoperative pancreatic juice secretion. Trypsinogen was activated by alkaline intestinal juice and then the nearby tissue was digested. Pancreatic juice flowed into abdominal cavity to digest the tissue, then caused serious complications or even death. Through the prevention of drugs, preoperative biliary drainage and intraoperative anastomosis, etc., the incidence of postoperative pancreatic fistula was slightly decreased. Conclusion The prevention for postoperative pancreatic fistula is an integrated process, and it needs to be ran through the whole perioperative period.
出处
《中国普外基础与临床杂志》
CAS
2015年第12期1530-1534,共5页
Chinese Journal of Bases and Clinics In General Surgery
基金
中国科学院"西部之光"人才培养计划项目(编号:2011-180)
中央高校基本科研业务费专项资金项目(编号:lzujbky-2012-163)~~
关键词
胰十二指肠切除术
胰瘘
术前减黄
预防
Pancreaticoduodenectomy
Pancreatic fistula
Preoperative biliary drainage
Prevention
