摘要
梗阻性黄疸可引起多器官、多系统损伤,如引起肝脏损伤,破坏肠黏膜屏障,导致肾衰竭,降低心肌收缩力,引起急性肺损伤,影响胰腺内外分泌功能等.其损伤机制比较复杂,是内毒素血症、氧自由基、细胞因子、胆汁成分等各种因素所致损伤的综合作用.
Jaundice can lead to multiple organ injury and multi-system damage, such as liver damage, intestinal barrier injury, renal failure, myocardial contractility decrease, acute lung injury, pancreatic endocrine and exocrine changes, etc. The mechanism of multiple organ injury in obstructive jaundice is complicated, which contains a variety of factors, like endotoxemia, oxygen free radicals, cytokines and bilirubin. In this article, we review the mechanism of multiple organ injury in obstructive jaundice.
出处
《腹部外科》
2015年第5期367-370,共4页
Journal of Abdominal Surgery
关键词
梗阻性黄疸
脏器损伤
内毒素血症
Obstructive jaundice
Multiple organ injury
Endotoxemia
